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| 1 | Prognostic implications for high expression of oncogenic microRNAs in advanced gastric carcinoma显示文摘 | Baek‐Hui Kim Soon Won Hong Aeree Kim Seung Ho Choi Sun Och Yoon | 2012 | J Surg Oncol2012，，5： | 1 |
| 2 | Ecological risk assessment of parent and halogenated polycyclic aromatic hydrocarbons in surface sediments from an urban river in south China显示文摘 | Jian‐Lin Sun Hong‐Gang Ni Hui Zeng | 2012 | Environmental Toxicology and Chemistry2012，，8： | 1 |
| 3 | Usefulness of Ki ‐67 ( MIB ‐1) immunostaining in the diagnosis of pulmonary sclerosing hemangiomas显示文摘 | Baek‐hui Kim Yoon‐sung Bae Se Hoon Kim Hyeong‐jae Jeong Soon Won Hong Sun Och Yoon | 2012 | APMIS2012，，2： | 1 |
| 4 | Deficiency of mitochondrial outer membrane protein 64 confers rice resistance to both piercing-sucking and chewing insects in rice显示文摘The brown planthopper(BPH)and striped stem borer(SSB)are the most devastating insect pests in rice(Oryza sativa)producing areas.Screening for endogenous resistant genes is the most practical strategy for rice insect-resistance breeding.Forty-five mutants showing high re-sistance against BPH were identified in a rice T-DNA in-sertion population(11,000 putative homozygous lines)after 4 years of large-scale field BPH-resistance phenotype screening.Detailed analysis showed that deficiency of rice mitochondrial outer membrane protein 64(OM64)gene resulted in increased resistance to BPH.Mitochondrial outer membrane protein 64 protein is located in the outer mitochondrial membrane by subcellular localization and its deficiency constitutively activated hydrogen peroxide(H2O2)signaling,which stimulated antibiosis and tolerance to BPH.The om64 mutant also showed enhanced resist-ance to SSB,a chewing insect,which was due to promotion of Jasmonic acid biosynthesis and related responses.Im-portantly,om64 plants presented no significant changes in rice yield-related characters.This study confirmed OM64 as a negative regulator of rice herbivore resistance through regulating H2O2 production.Mitochondrial outer membrane protein 64 is a potentially efficient candidate to improve BPH and SSB resistance through gene deletion.Why the om64 mutant was resistant to both piercing-sucking and chewing insects via a gene deficiency in mitochondria is discussed. | Hui‐Min Guo Hai‐Chao Li Shi‐Rong Zhou Hong‐Wei Xue Xue‐Xia Miao | 2020 | Journal of Integrative Plant Biology2020，62，12： | 1 |
| 5 | Epidemiological survey and risk factor analysis of fatty liver disease of adult residents, B eijing, C hina显示文摘 | Jie Yan Wen Xie Wei‐ni Ou Hong Zhao Su‐yun Wang Jian‐hui Wang Qi Wang Yu‐ying Yang Xin Feng Jun Cheng | 2013 | J Gastroenterol Hepatol2013，，10： | 3 |
| 6 | miR‐93/Sp7 function loop mediates osteoblast mineralization显示文摘 | Li Yang Peng Cheng Chao Chen Hong‐Bo He Gen‐Qing Xie Hou‐De Zhou Hui Xie Xian‐Ping Wu Xiang‐Hang Luo | 2012 | J Bone Miner Res2012，，7： | 2 |
| 7 | Long‐term outcomes of short dental implants supporting single crowns in posterior region: a clinical retrospective study of 5–10 years显示文摘 | Hong‐Chang Lai Mi‐Si Si Long‐Fei Zhuang Hui Shen Yue‐lian Liu Daniel Wismeijer | 2012 | Clin. Oral Impl. Res2012，，2： | 1 |
| 8 | Chemoprevention of intestinal adenomatous polyposis by acetyl‐11‐keto‐beta‐boswellic acid in APC <sup> Min /+</sup> mice显示文摘 | Hui‐Ping Liu Zu‐Hua Gao Shu‐Xiang Cui Yan Wang Bao‐Ying Li Hong‐Xiang Lou Xian‐Jun Qu | 2012 | Int J Cancer2012，，11： | 1 |
| 9 | Molecular epidemiology of Echovirus 30 in Fujian, China between 2001 and 2011显示文摘 | Xiu‐hui Yang Yan‐sheng Yan Yu‐wei Weng Ai‐hua He Hong‐rong Zhang Wei Chen Yong Zhou | 2013 | J. Med. Virol2013，，： | 1 |
| 10 | Enhanced Secretion of Heterologous Proteins in Pichia pastoris Following Overexpression of Saccharomyces cerevisiae Chaperone Proteins显示文摘 | WeiZhang Hong‐liangZhao ChongXue Xiang‐huaXiong Xue‐qinYao Xian‐yuLi Hui‐pengChen Zhi‐minLiu | 2008 | Biotechnol Progress2008，，4： | 1 |
| 11 | HSCs play a distinct role in different phases of oval cell‐mediated liver regeneration显示文摘 | Lin Chen Wei Zhang Qiao‐dan Zhou Hong‐qiang Yang Hui‐fang Liang Bi‐xiang Zhang Xin Long Xiao‐ping Chen | 2012 | Cell Biochem Funct2012，，7： | 1 |
| 12 | Preparation and characterization of a composite nanofiltration membrane from cyclen and trimesoyl chloride prepared by interfacial polymerization显示文摘 | Gui‐E. Chen Yan‐Jun Liu Zhen‐Liang Xu Deng Hu Hui‐Hong Huang Li Sun | 2015 | J. Appl. Polym. Sci2015，，33： | 1 |
| 13 | HSCs play a distinct role in different phases of oval cell‐mediated liver regeneration显示文摘 | Lin Chen Wei Zhang Qiao‐dan Zhou Hong‐qiang Yang Hui‐fang Liang Bi‐xiang Zhang Xin Long Xiao‐ping Chen | 2012 | Cell Biochem Funct2012，，： | 1 |
| 14 | A novel role for cyanide in the control of cucumber ( Cucumis sativus L.) seedlings response to environmental stress显示文摘 | FEI XU DA‐WEI ZHANG FENG ZHU HE TANG XIN LV JIAN CHENG HUANG‐FAN XIE HONG‐HUI LIN | 2012 | Plant, Cell & Environment2012，，11： | 1 |
| 15 | SP1 mediates the link between methylation of the tumour suppressor miR‐149 and outcome in colorectal cancer显示文摘 | Feng Wang Yan‐Lei Ma Peng Zhang Tong‐Yi Shen Chen‐Zhang Shi Yong‐Zhi Yang Mary‐Pat Moyer Hui‐Zhen Zhang Hong‐Qi Chen Yong Liang Huan‐Long Qin | 2012 | J Pathol2012，，1： | 1 |
| 16 | HOTAIR , a prognostic factor in esophageal squamous cell carcinoma, inhibits WIF ‐1 expression and activates W nt pathway显示文摘 | Xiao‐Song Ge Hua‐Juan Ma Xiao‐Hui Zheng Hong‐Lian Ruan Xiao‐Yu Liao Wen‐Qiong Xue Yuan‐Bin Chen Ying Zhang Wei‐Hua Jia | 2013 | Cancer Sci2013，，12： | 1 |
| 17 | Molecular and structural characterization of a promiscuous chalcone synthase from the fern species Stenoloma chusanum显示文摘The key enzymes involved in the flavonoid biosynthesis pathway have been extensively studied in seed plants,but relatively less in ferns.In this study,two 4-Coumarate:coenzyme A ligases(Sc4CL1 and Sc4CL2)and one novel chalcone synthase(ScCHS1)were functionally characterized by mining the Stenoloma chusanum transcriptome database.Recombinant Sc4CLs were able to esterify various hydroxycinnamic acids to corresponding acyl-coenzyme A(CoA).ScCHS1could catalyze p-coumaroyl-CoA,cinnamoyl-CoA,caffeoyl-CoA,and feruloyl-CoA to form naringenin,pinocembrin,eriodictyol,and homoeriodictyol,respectively.Moreover,enzymatic kinetics studies revealed that the optimal substrates of ScCHS1were feruloyl-CoA and caffeoyl-CoA,rather than p-coumaroyl-CoA,which was substantially different from the common CHSs.Crystallographic and sitedirected mutagenesis experiments indicated that the amino acid residues,Leu87,Leu97,Met165,and Ile200,located in the substrate-binding pocket near the B-ring of products,could exert a significant impact on the unique catalytic activity of ScCHS1.Furthermore,overexpression of ScCHS1 in tt4 mutants could partially rescue the mutant phenotypes.Finally,ScCHS1 and Sc4CL1 were used to synthesize flavanones and flavones with multi-substituted hydroxyl and methoxyl B-ring in Escherichia coli,which can effectively eliminate the need for the cytochrome P450 hydroxylation/O-methyltransferase from simple phenylpropanoid acids.In summary,the identification of these important Stenoloma enzymes provides a springboard for the future production of various flavonoids in E.coli. | Rong Ni Meng Niu Jie Fu Hui Tan Ting‐Ting Zhu Jing Zhang Hong‐Xiang Lou Peng Zhang Jian‐Xu Li Ai‐Xia Cheng | 2022 | Journal of Integrative Plant Biology2022，64，10： | 1 |
| 18 | miR‐148a regulates osteoclastogenesis by targeting V‐maf musculoaponeurotic fibrosarcoma oncogene homolog B显示文摘 | Peng Cheng Chao Chen Hong‐Bo He Rong Hu Hou‐De Zhou Hui Xie Wu Zhu Ru‐Chun Dai Xian‐Ping Wu Er‐Yuan Liao Xiang‐Hang Luo | 2013 | J Bone Miner Res2013，，5： | 1 |
| 19 | Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma显示文摘 | Bo Hui Ying‐Hong Shi Zhen‐Bin Ding Jian Zhou Cheng‐Yu Gu Yuan‐Fei Peng Hua Yang Wei‐Ren Liu Guo‐Ming Shi Jia Fan | 2012 | Cancer2012，，22： | 1 |
| 20 | Favorable prognosis of biallelic CEBPA gene mutations in acute myeloid leukemia patients: a meta‐analysis显示文摘 | Hong‐Ying Li Dong‐Hong Deng Ying Huang Fang‐Hui Ye Lu‐Lu Huang Qiang Xiao Bing Zhang Bing‐Bing Ye Yong‐Rong Lai Zeng‐Nan Mo Zhen‐Fang Liu | 2015 | Eur J Haematol2015，，： | 1 |
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