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| 1 | Role of polyethylene particles in peri-prosthetic osteolysis:A review显示文摘There is convincing evidence that particles produced by the wear of joint prostheses are causal in the periprosthetic loss of bone,or osteolysis,which,if it progresses,leads to the phenomenon of aseptic loosening.It is important to fully understand the biology of this bone loss because it threatens prosthesis survival,and loosened implants can result in peri-prosthetic fracture,which is disastrous for the patient and presents a difficult surgical scenario.The focus of this review is the bioactivity of polyethylene(PE)particles,since there is evidence that these are major players in the development and progression of osteolysis around prostheses which use PE as the bearing surface.The review describes the biological consequences of interaction of PE particles with macrophages,osteoclasts and cells of the osteoblast lineage,including osteocytes.It explores the possible cellular mechanisms of action of PE and seeks to use the findings to date to propose potential nonsurgical treatments for osteolysis.In particular,a nonsurgical approach is likely to be applicable to implants containing newer,highly cross-linked PEs(HXLPEs),for which osteolysis seems to occur with much reduced PE wear compared with conventional PEs.The caveat here is that we know little as yet about the bioactivity of HXLPE particles and addressing this constitutes our next challenge. | Gerald J Atkins David R Haynes Donald W Howie David M Findlay | 2011 | World Journal of Orthopedics2011，2，10： | 11 |
| 2 | Reninoma: case report and literature review显示文摘 | Lara Wong Thomas HS Hsu Mark G Perlroth Lawrence V Hofmann Claudia M Haynes Laurence Katznelson | 2008 | Journal of Hypertension2008，，2： | 2 |
| 3 | On the 'downward control'of extratropical diabatic circulations by eddy-induced mean zonal forces显示文摘 | Haynes P H C J Marks M E McIntyre | 1991 | J Atmoa Sci1991，48，： | 1 |
| 4 | A prospective study of the effect of haemorrhoideetomy on sphincter function and faecal continence显示文摘 | Read N W Haynes W G | 1982 | Br J Surg1982，69，7： | 1 |
| 5 | The relationship of the number of Meissner's corpuscles to dermatoglyphic characters and finger size显示文摘 | Dillon YK Haynes J Henneberg M | 2001 | Journal of Anatomy2001，199，5： | 1 |
| 6 | Continuous-mixtures vapor-liquid equilibria computations based on true boiling point distillations 显示文摘 | HAYNES H W MATHEWS M A | 1991 | Ind Eng Chem Res1991，30，： | 1 |
| 7 | Target isolation for SAR images显示文摘 | Xu R Kwan C M Haynes L S | 2001 | Proceedings of SPIE2001，4382，： | 1 |
| 8 | Some effects of orchards soil management on sward composition levels of available nutrients in the soil and leaf nutrient content of nature 'Golden Delicious' apple trees显示文摘 | Haynes R J K M Goh | 1980 | SciHort1980，13，： | 1 |
| 9 | High-level intracellular expregsion of hydroxynitrile lyase from the tropical rubber tree Hevea brasiliensis in microbial hosts显示文摘 | Hasslacher M Schall M Hayn M | 1999 | Protein Expr Purif1999，11，： | 1 |
| 10 | Total domination subdivision numbers of trees显示文摘 | Haynes T W Henning M A Hopkins L | 2004 | Discrete Mathematics2004，286，： | 1 |
| 11 | Affinity-enhanced protein partitioning in decyl beta-D-glucopyranoside twophase aqueous micellar systems显示文摘 | Kavoosi M Haynes C A | 2005 | Biotechnol Bioeng2005，89，： | 1 |
| 12 | Liposomal delivery of doxorubicin to hepatocytes in vivo by targeting heparan sulfate 显示文摘 | LONGMUIR K J HAYNES S M BARATTA J L | 2009 | lnt J Pharm2009，382，12： | 1 |
| 13 | Salt weathering distress on concrete exposed to sodium sulfate environment 显示文摘 | Haynes H O’Neill R Neff M | 2008 | J ACI Mater2008，105，1： | 1 |
| 14 | The Impact of Divestment on Firm Performance:Empirical Evidence from a Panel of UK Companies显示文摘 | Haynes M and others | 2002 | The Journal of Industrial Econmics2002，，50： | 1 |
| 15 | Magneto-optical study of electron occupation and hole wave functions in stacked self-assembled InP quantum dots显示文摘 | Hayne M Maes J Manz Y M | 2001 | Appl Phys Lett2001，，79： | 1 |
| 16 | Cooper degradation of misfolded proteins prevents ER-derived oxidative stress and cell death显示文摘 | Haynes C M Titus E A Antony A | 2004 | Molecular Cell2004，15，： | 1 |
| 17 | Thermal cycling behavior of plasma-sprayed thermal barrier coatings with various MCrAIX bond coats显示文摘 | Haynes J A Ferber M K Porter W D | | 0，，01： | 1 |
| 18 | On the 'downward control'of the extratropical diabatic circulations by eddy-induced mean zonal forces显示文摘 | Haynes P H M E Marks T G Shepherd | 1991 | J Atmos Sci1991，48，： | 1 |
| 19 | Nanosphere lithography: tunable localized surface plasmon resonance spectra of silver nanoparticles显示文摘 | Jensen T R Malinsky M D Haynes C L | 2000 | Journal of Physical Chemistry B2000，104，10： | 1 |
| 20 | Successful treatment of sudden hearing loss in Cogan′s syndrome with corticosteroids显示文摘 | Pikus A Kaiser-Kupfer M | 1981 | Arthritis Rheum1981，24，3： | 1 |
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