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886篇 您的检索式:作者名="HAMMOND E E"
    题名 作者 年代 出处 被引量
1Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly 2012Cellular & Molecular Immunology2012,9,3:3
2Role for a bidentate ribonuclease in the initiation step of RNA interference显示文摘Bernstein E Caudy A A Hammond S M 2001Nature2001,409,6818:2
3Role for a bidentate ribonuelease in the initiation step of RNA interference 显示文摘Bernstein E Caudy AA Hammond SA 2001Nature2001,409,:1
4Purine and pyrimidine metabolism in the Trypansosmatidae显示文摘Hammond D J Gutteridge W E 1984Mol Biochem Parasitol1984,13,:1
5Infection with Chlamydia pneumoniae accelerates the development of atherosclerosis and treatment with azithromycin prevents it in a rabbit mode 显示文摘Muhlestein J B Anderson J L Hammond E H 1998Circulation1998,97,:1
6The development of inhibitors of heparanase, a key enzyme involved in tumour metastasis, angiogenesis and inflammation 显示文摘Ferro V Hammond E Fairweather J K 2004Mini Rev Med Chem2004,4,6:1
7Universal amplification and analysis of pathogen 16S rRNA for classification and identification of mycoplasmalike organisms 显示文摘Lee I M Hammond R W Davis R E 1993Phytopathology1993,83,8:1
8An RNA-directed nuclease mediates post-transcriptional gene silencing in drosophila cells 显示文摘Hammond SM Bemstein E Beach D 2000Nature2000,404,6775:1
9An RNA-directod nuclease mediates post-transcriptional gone silencing in Drosophila cells显示文摘Hammond SM Bernstein E Beach D 0,,6757:1
10American Socie- ty o Clinical Oncology / College o显示文摘Wolff A C Hammond M E Schwartz J N 2007Arch Pathol Lab Med2007,131,1:1
11An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells显示文摘Hammond S M Bernstein E Beach D 2000Nature2000,404,:1
12Renal deposition of cy- tomegalovirus antigen in immunoglobulin-A nephropathy 显示文摘Gregory M C Hammond M E Brewer E D 1988Lancet1988,1,85756:1
13An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells显示文摘Hammond SM Bernstein E Beach D 2000Nature2000,404,6775:1
14Role for a bidentate ribonuclease in the initiation step of RNA interference显示文摘Bernstein E Caudy A A Hammond S M 2001Nature2001,409,:1
15Role for a bidentate ribonuclease in the initiation step of RNA interference显示文摘Bernstein E Caudy AA Hammond S 2001Nature2001,409,:1
16Role for a bidentate ribonuclease in the initiation step of RNA interference显示文摘Bernstein E Caudy AA Hammond SM 0,,:1
17Role for a bidentate ribonuclease in the initiation step of RNA interfer- ence显示文摘Bernstein E Caudy A A Hammond S M 2001Nature2001,409,:1
18An RNA-directedmuciease mediates post-transcriptional gene silencing in Drosophlla cells显示文摘 Bemstain E Beach D 2000Nature2000,404,:1
19Role for a bidentate ribonuclease in the initiation step of RNA interference显示文摘 CAUDY A A HAMMOND S M 2001Nature2001,409,6818:1
20Role for a Bidentate Ribonuclease in the Initiation Step of RNA Interfer- ence 显示文摘BERNSTEIN E CAUDY A HAMMOND S 2001Nature2001,409,6818:1
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