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| 1 | Incident frailty and cognitive impairment by heart failure status in older patients with atrial fibrillation: the SAGE-AF study显示文摘Background Atrial fibrillation(AF) and heart failure(HF) frequently co-occur in older individuals. Among patients with AF, HF increases risks for stroke and death, but the associations between HF and incident cognition and physical impairment remain unknown. We aimed to examine the cross-sectional and prospective associations between HF, cognition, and frailty among older patients with AF. Methods The SAGE-AF(Systematic Assessment of Geriatric Elements in AF) study enrolled 1244 patients with AF(mean age 76 years, 48% women) from five practices in Massachusetts and Georgia. HF at baseline was identified from electronic health records using ICD-9/10 codes. At baseline and 1-year, frailty was assessed by Cardiovascular Health Survey score and cognition was assessed by the Montreal Cognitive Assessment. Results Patients with prevalent HF(n = 463, 37.2%) were older, less likely to be non-Hispanic white, had less education, and had greater cardiovascular comorbidity burden and higher CHA2 DS2 VASC and HAS-BLED scores than patients without HF(all P's < 0.01). In multivariable adjusted regression models, HF(present vs. absent) was associated with both prevalent frailty(adjusted odds ratio [a OR]: 2.38, 95% confidence interval [CI]: 1.64-3.46) and incident frailty at 1 year(a OR: 2.48, 95% CI: 1.37-4.51). HF was also independently associated with baseline cognitive impairment(a OR: 1.60, 95% CI: 1.22-2.11), but not with developing cognitive impairment at 1 year(a OR 1.04, 95%CI: 0.64-1.70). Conclusions Among ambulatory older patients with AF, the co-existence of HF identifies individuals with physical and cognitive impairments who are at higher short-term risk for becoming frail. Preventive strategies to this vulnerable subgroup merit consideration. | Wei-Jia WANG Darleen Lessard Jane Saczynski Robert J Goldberg Alan S.Go Tenes Paul Ely Gracia David D McManus | 2020 | Journal of Geriatric Cardiology2020，17，11： | 2 |
| 2 | Enhancement of fault injection techniques based on the modification of VHDL code 显示文摘 | Baraza J C Gracia J Blanc S | 2008 | IEEE Transactions on Very Large Scale Integration (VLSI) Systems2008，16，6： | 1 |
| 3 | Optical and crystallization behavior of TiO2 and V/TiO2 thin films prepared by plasma and ion beam assisted methods显示文摘 | Holgado J P Contreras L | 2003 | Thin Solid films2003，429，12： | 1 |
| 4 | TiO2-catalysed ozonation of raw Ebro river water显示文摘 | Cortes S Sarasa J | 2000 | Water Res2000，34，： | 1 |
| 5 | DFT study of the reaction between VO+ and C2H6 显示文摘 | Gracia L Andres J Safont V S | 2004 | Organometallics2004，23，： | 1 |
| 6 | Prospective randomized trial comparing conventional laparoscopic colectomy with hand--assisted laparoscopic colectomy:pplicability,immediate clinical outcome,inflammatory response,and cost显示文摘 | Targarona EM Gracia E Garriga J | 2002 | Surg Endosc2002，16，2： | 1 |
| 7 | Alpha-amylase supplementation of broiler diets based on corn显示文摘 | Gracia M I Aranibar M J Lazaro R | 2003 | Poultry Science2003，82，： | 1 |
| 8 | Trace metals in the bivalve mollusks Chamelea gallina from the Atlantic coast of southem Spain显示文摘 | Usero J Gonzalez-Regalado E Gracia I | 1996 | Marine Pollution Bulletin1996，32，： | 1 |
| 9 | Trace metal in the bivalve molluscs Ruditapes decussatus and Ruditapes phil- ippinarum from the Atlantic coast of southern Spain 显示文摘 | USERO J GONZALEZ- REGALADO E GRACIA I | 1997 | Environ Intern1997，23，3： | 1 |
| 10 | Diagnostic value of bronchoalveclar lavage in suspected pulmonary tuberculosis 显示文摘 | De Gracia J | 1988 | Chest1988，93，： | 1 |
| 11 | Dielectrophoretic Assembly of Reversible and Irreversible Metal Nanowire Networks and Vertically Aligned Arrays显示文摘 | Papadakis S J Gu z Gracias D H | 2006 | Applied Physics Letters2006，88，23： | 1 |
| 12 | Expectant management of severe preeclampsia and preeclampsia superimposed on chronic hypertension between 24 and 34 weeks' gestation显示文摘 | Vigil-De Gracia P Montufar-Rueda C Ruiz J | | 0，，01： | 1 |
| 13 | Multidimensional approach to non-cystic fibrosis hronchiectasis: the FACED score 显示文摘 | Martinez-Garcia MA de Gracia J Vendrell RM | 2014 | Eur Respir J2014，43，5： | 1 |
| 14 | Ovarian tissue cryopreservation for fertility preservation in cancer patients: successful establishment and feasibility of a multidisciplinary collaboration显示文摘 | Gracia CR Chang J Kondapalli L | 2012 | J Assist Reprod Genet2012，29，6： | 1 |
| 15 | Kinetics, FTIR, and controlled atmosphere EXAFS study of the effect of chlorine on ptsupported catalysts during oxidation reactions显示文摘 | GRACIA F J MILLER J T KROPF A J WOLF E E | 2002 | J Catal2002，209，2： | 1 |
| 16 | Do oil price shocks matter'? evidence tbr some European countries 显示文摘 | Cunado J de Gracia F P | 2003 | Energy Economics2003，25，： | 1 |
| 17 | Mn(Ⅱ)-catalysed ozonation of raw ebro river water and its ozonation by-products显示文摘 | Gracia R Aragues J L Ovelleiro J L | 1998 | Water Research1998，32，1： | 1 |
| 18 | Strategies to enhance the carbon monoxide sensitivity of tin oxide thin films 显示文摘 | Mandayo G G Castao E Gracia F J | 2003 | Sens Actuators B2003，，95： | 1 |
| 19 | Phase mixing in Fe/TiO2 thin films prepared by ion beam-induced chemical vapour deposition:optical and structural properties显示文摘 | Gracia F Holgado J Yubero F | 2002 | Surface and Coatings Technology2002，，： | 1 |
| 20 | TiO2-catalysed ozonation of raw Ebro river water 显示文摘 | Gracia R Corts S Sarasa J | 2000 | Wat Res2000，34，5： | 1 |
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