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| 1 | The effects of Spirulina on anemia and immune function in senior citizens显示文摘Anemia and immunological dysfunction(i.e.immunosenescence)are commonly found in older subjects and nutritional approaches are sought to counteract these phenomena.Spirulina is a filamentous and multicellular bule-green alga capable of reducing inflammation and also manifesting antioxidant effects.We hypothesized that Spirulina may ameliorate anemia and immunosenescence in senior citizens with a history of anemia.We enrolled 40 volunteers of both sexes with an age of 50 years or older who had no history of major chronic diseases.Participants took a Spirulina supplementation for 12 weeks and were administered comprehensive dietary questionnaires to determine their nutritional regimen during the study.Complete cell count(CCC)and indoleamine 2,3-dioxygenase(IDO)enzyme activity,as a sign of immune function,were determined at baseline and weeks 6 and 12 of supplementation.Thirty study participants completed the entire study and the data obtained were analyzed.Over the 12-week study period,there was a steady increase in average values of mean corpuscular hemoglobin in subjects of both sexes.In addition,mean corpuscular volume and mean corpuscular hemoglobin concentration also increased in male participants.Older women appeared to benefit more rapidly from Spirulina supplements.Similarly,the majority of subjects manifested increased IDO activity and white blood cell count at 6 and 12 weeks of Spirulina supplementation.Spirulina may ameliorate anemia and immunosenescence in older subjects.We encourage large human studies to determine whether this safe supplement could prove beneficial in randomized clinical trials. | Carlo Selmi Patrick SC Leung Laura Fischer Bruce German Chen-Yen Yang Thomas P Kenny Gerry R Cysewski M Eric Gershwin | 2011 | Cellular & Molecular Immunology2011，8，3： | 2 |
| 2 | MODIFIED MELT TEXTURING PROCESS FOR YBCO BASED ON THE POLYTHERMIC SECTION YO1.5-BA0.4CU0.6O IN THE Y-BA-CU-O PHASE DIAGRAM AT 0.21 BAR OXYGEN PRESSURE显示文摘 | Krabbes G Schatzle P Bieger W Wiesner U Stover G Wu M Strasser T Litzkendorf D Fischer K Gornert P | | 0，，： | 2 |
| 3 | Development of high performance multifilamentary Nb-Ti-Ta superconductor for LHC insertion quadrupoles 显示文摘 | Lee P J Fischer C M Larbalestier D C | 1999 | IEEE Trans Applied Superconductivity1999，9，2： | 1 |
| 4 | Information, contracting and quality costs 显示文摘 | Baiman S Fischer P E Rajah M V | 2000 | Management Science2000，46，6： | 1 |
| 5 | Project-modelling inAEC to integrate design and construction显示文摘 | Luiten G T Tolman F P Fischer M A | 1998 | Computers inIndustry1998，，35： | 1 |
| 6 | Biodegradable magnesium-hydroxyapatite metal matrix composites显示文摘 | WITTE F FEYERABEND F MAIER P FISCHER J STORMER M BLAWERT C DIETZEL W HORT N | 2007 | Biomaterials2007，28，： | 1 |
| 7 | Parturition at term:parallel increases in interleukin-8 and proteinase concentrations and neutrophil count in the lower uterine segment显示文摘 | Winkler M Fischer D C Ruck P | 1999 | Hum Reprod1999，14，： | 1 |
| 8 | Biodegradable starch/day nanocomposite films for food packaging applications显示文摘 | Avella M De Vlieger J J Erfico M E Fischer S Vacca P & Volpe M G | 2005 | Food Chemistry2005，93，： | 1 |
| 9 | Spatial growthregressions: Model specification, estimation andinterpretation显示文摘 | LESAGE J P FISCHER M M | 2007 | Spatial Economic Analysis2007，3，3： | 1 |
| 10 | Gas analysis by infra- red spectroscopy as a tool for electrical fault diagnostics in SF~ insulated equipment显示文摘 | Heise H M Kurte R Fischer P | 1997 | Fresenius Journal of Analytical Chem istry1997，358，5： | 1 |
| 11 | Impaired behaviour,learning and memory,in adult mice neonatally exposed to hexabromocy-clododecane(HBCD)显示文摘 | ERIKSSON P FISCHER C WALLIN M | 2006 | Environmental Toxicology andPharmacology2006，21，3： | 1 |
| 12 | Evaluation of wheat polyphenol oxidase genes 显示文摘 | Jukanti A K Bruekner P L Fischer A M | 2004 | Cereal Chemistry2004，81，： | 1 |
| 13 | Gas analysis by infrared spectroscopy as a tool for electrical fault diagnostics in SF6 insulated equipment显示文摘 | HEISE H M KURTE R FISCHER P | 1997 | Fresenius'' Journal of Analytical Chemistry1997，，9358： | 1 |
| 14 | Information, contracting, and quality costs显示文摘 | Baiman S Fischer P E Rajan M V | 2000 | Management Science2000，46，6： | 1 |
| 15 | Uncertainty Budgets for Calibration of Radiation Thermometers below the Silver Point 显示文摘 | Saunders P Fischer J Sadli M | 2008 | Int J Thermophys2008，29，3： | 1 |
| 16 | Noncovalent interm olecular forces in p o lycrystallin e and amorphous saccharides in thefar in frared显示文摘 | W alther M Fischer B M Jepsen P U | 2003 | Ch em ical P h y sics2003，288，2： | 1 |
| 17 | The effect of dietary zinc on intestinal copper absorption 显示文摘 | Fischer P W F Giroux A and L' Abbe M R | 1981 | Am J Clin Nutr1981，34，16： | 1 |
| 18 | Dimagnesium iron (Ⅱ) hydride, MgzFeH6, containing octahedral Feh6^4- anions 显示文摘 | DIDISHEIM J J ZOLLIKER P YVON K FISCHER P SCHEFER J GUBELMANN M | 1984 | Inorg Chem1984，23，： | 1 |
| 19 | Desmoid tumours of the abdominal wall: a case report 显示文摘 | Overhaus M Decker P Fischer HP | 2003 | World J Surg Oncol2003，1，1： | 1 |
| 20 | Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE) 显示文摘 | Raaschou-Nielsen 0 Andersen ZJ Beelen R Samoli E Stafoggia M Weinmayr G Hoffmann B Fischer P Nieuwenhuijsen MJ Brunekreef B Xun WW Katsouyanni K Dimakopoulou K Sommar J Forsberg B Modig L Oudin A Oftedal B Schwarze PE Nafstad p De Faire U Pedersen NL Ostenson CG Fratiglioni L Penell J Korek M Pershagen G Eriksen KT Serensen M Tjenneland A Ellermann T Eeftens M Peeters PH Meliefste K Wang M Bueno-de-Mesquita B Key TJ de Hoogh K Concin H Nagel G Yilier A Grioni S Krogh y Tsai MY Ricceri F Sacerdote C Galassi C Migliore E Ranzi A Cesaroni G Badaloni C Forastiere F Tamayo I Amiano P Dorronsoro M Trichopoulou A Bamia C Yineis p Hoek G | 2013 | Lancet Oncol2013，14，9： | 1 |
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