维普中文期刊产品整合服务
549篇 您的检索式:作者名="Delgado E"
    题名 作者 年代 出处 被引量
1高血压患者脑小血管病变化对认知功能的影响显示文摘高血压是脑小血管病进展与认知功能障碍的主要危险因素之一。该研究旨在探讨高血压患者脑小血管病损伤变化与认知功能减退及轻度认知功能障碍的关系。该研究的数据从ISSYS队列(探讨高血压无症状性脑卒中:一个磁共振成像研究)中获得,其是一项纵向人群研究,纳入基线无痴呆及脑卒中,年龄50~70岁的高血压患者。Jiménez-Balado J Riba-Llena I Abril O Garde E Penalba A Ostos E Maisterra O Montaner J Noviembre M Mundet X Ventura O Pizarro J Delgado P 赵狄 练桂丽 2019中华高血压杂志2019,27,2:15
2Mitochondrial protection by low doses of insulin-like growth factor-Ⅰin experimental cirrhosis显示文摘AIM: To characterize the mitochondrial dysfunction in experimental cirrhosis and to study whether insulin-like growth factor-Ⅰ(IGF-Ⅰ) therapy (4 wk) is able to induce beneficial effects on damaged mitochondria leading to cellular protection. METHODS: Wistar rats were divided into three groups: Control group, untreated cirrhotic rats and cirrhotic rats treated with IGF-Ⅰtreatment (2 μg/100 g bw/d). Mitochondrial function was analyzed by flow cytometry in isolated hepatic mitochondria, caspase 3 activation was assessed by Western blot and apoptosis by TUNEL in the three experimental groups. RESULTS: Untreated cirrhotic rats showed a mitochon- drial dysfunction characterized by a significant reduction of mitochondrial membrane potential (in status 4 and 3); an increase of intramitochondrial reactive oxigen species (ROS) generation and a significant reduction of ATPase activity. IGF-Ⅰtherapy normalized mitochondrial func-tion by increasing the membrane potential and ATPase activity and reducing the intramitochondrial free radical production. Activity of the electron transport complexes Ⅰand Ⅲ was increased in both cirrhotic groups. In addition, untreated cirrhotic rats showed an increase of caspase 3 activation and apoptosis. IGF-Ⅰtherapy reduced the expression of the active peptide of caspase 3 and resulted in reduced apoptosis.Raquel Pérez María García-Fernández Matías Díaz-Sánchez Juan E Puche Gloria Delgado Marian Conchillo Jordi Muntané Inma Castilla-Cortázar 2008World Journal of Gastroenterology2008,14,17:11
3Role of vasoactive intestinal peptide in inflammation and autoimmunity显示文摘Gonzalez-Rey E Delgado M 2005Curr Opin Investig Drugs2005,6,11:1
4PEGylation of cytokines and other therapeutic proteins and peptides: the importance of biological optimization of coupling techniques 显示文摘Francis C E Fisher D Delgado C 1998Int J Hematol1998,68,3:1
5A communication model based on the 2-tuple fuzzy linguistic representation for a distributed intelligent agent system on Intemet显示文摘Delgado M Herrera F Herrera-Viedma E 2002Soft Computing-A Fusion of Foundations Methodologies and Applications2002,6,5:1
6Impact of age and colony-stimulating factor use on hospital length of stay for febrile neutropenia in CHOP-treated non-Hodgkin' s lymphoma 显示文摘Chrischilles E Delgado DJ Stolshek BS 2002Cancer Control2002,9,3:1
7U- niportal video-assisted thoracoscopic lobeaolny 显示文摘GONZALEZ-RIVAS D FIEIRA E DELGADO M 2013J Thoracic Dis2013,5,3:1
8Acarbose improves indirectly both insulin resistance and secretion in obese type 2 diabetic patients 显示文摘Delgado H Lehmann T BobbioniHarsch E 2002Diabetes Metab2002,28,3:1
9Th2 lymphocytes secrete functional VIP upon antigen stimulation显示文摘Vassiliou E Jiang X Delgado M 2001Arch Physiol Biochem2001,109,4:1
10Double sleeve uniportal video-assisted thoracoscopic lobectomy for non-small cell lung cancer 显示文摘GONZALEZ'-RIVAS D DELGADO M FIEIRA E 2014Ann Car- diothorac Surg2014,3,2:1
11Guidelines for withholding or termination of resuscitation in prehospital traumatic cardiopulmonary arrest: joint position statement of the National Association of EMS Physicians and the American College of Surgeons Committee on Trauma显示文摘Hopson LR Hirsh E Delgado J 2003J Am Coll Surg2003,196,1:1
12Variants of peach latent mosaic viroid inducing peach calico:uneven distribution in infected plants and requirements of the insertion containing the pathogenicity determinant显示文摘 Delgado S Flores R 2006J Gen Virol2006,87,:1
13Regulation of dendritic cell differentiation by vasoactive intestinal pep tide: therapeutic applications on autoimmunity and transplantation显示文摘Chorny A Gonzalez-Rey E Delgado M 2006Ann N Y Acad Sci2006,1088,:1
14The calpain system in three muscles of normal andcallipyge sheep显示文摘DELGADO E F 2001Journal of Animal Science2001,79,:1
15Brand trust in the context of consumer loyalty 显示文摘Delgado Ballester E Munuera-Aleman J L 2001European Journal of mar- keting2001,35,1112:1
16Abnormalities in the expression of CD55 and CD59 surface molecules on peripheral blood cells are not specific to paroxysmal nocturnal hemoglobinuria显示文摘Ruiz Delgado G J Vzquez Garza E Mndez Ramrez N 0,,01:1
17Guidelines for withholding or termination of resuscitation in prehospital traumatic cardiopulm- onary arrest :joint position statement of the National Association of EMS Physicians and the American College of Surgeons Committee on Tranma显示文摘Hopson LR Himh E Delgado J et ai 2003J Am Coil Sufg2003,196,1:1
18Defining Clusters of Related In- dustries 显示文摘Delgado M Poter M E Stern S 2015Journal of Economic Geography2015,,3:1
19Properties of myofibril-bound calpain activity in long- issimus muscle of callipyge and normal sheep显示文摘DELGADO E F 2001Journal of Animal Science2001,79,:1
20Advanced CT imaging in the evaluation of hemorrhagic stroke显示文摘Delgado A J E Romero J M 2011Neuroimaging Clinics of North America2011,21,2:1
返回顶部 每页显示:
共28页 首页 上一页 第1页 下一页 末页 /28 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费