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	题名	作者	年代	出处	被引量
1	In vivo radiometric analysis of glucose uptake and distribution in mouse bone显示文摘Bone formation and remodeling occurs throughout life and requires the sustained activity of osteoblasts and osteoclasts,particularly during periods of rapid bone growth.Despite increasing evidence linking bone cell activity to global energy homeostasis,little is known about the relative energy requirements or substrate utilization of bone cells.In these studies,we measured the uptake and distribution of glucose in the skeleton in vivo using positron-emitting^(18)F-fluorodeoxyglucose([^(18)F]-FDG) and non-invasive,high-resolution positron emission tomography/computed tomography(PET/CT) imaging and ex vivo autoradiography.Assessment of [^(18)F]-FDG uptake demonstrated that relative to other tissues bone accumulated a significant fraction of the total dose of the glucose analog.Skeletal accumulation was greatest in young mice undergoing the rapid bone formation that characterizes early development.PET/CT imaging revealed that [^(18)F]-FDG uptake was greatest in the epiphyseal and metaphyseal regions of long bones,which accords with the increased osteoblast numbers and activity at this skeletal site.Insulin administration significantly increased skeletal accumulation of [^(18)F]-FDG,while uptake was reduced in mice lacking the insulin receptor specifically in osteoblasts or fed a high-fat diet.Our results indicated that the skeleton is a site of significant glucose uptake and that its consumption by bone cells is subject to regulation by insulin and disturbances in whole-body metabolism.	Meredith L Zoch Diane S Abou Thomas L Clemens Daniel LJ Thorek Ryan C Riddle	2016	Bone Research2016，4，1：	9
2	Use of double-stranded RNA interference in Drosophila cell lines to dissectsignal trans duction pathways显示文摘	Clemens J C Worby C A	2000	Proc Natl Acad Sci USA2000，97，12：	1
3	Processes controlling the geo- chemical composition of the South China Sea sediments during the last climatic cycle显示文摘	Sun Y Wu F Clemens S C	2008	Chemical Geology2008，257，：	1
4	Air and gas pockets in sewerage pressure mains显示文摘	Lubbers C L Clemens F	2005	Water Science and Technology2005，52，3：	1
5	Autoinduction of the trefoil factor 2 (TFF2) promoter requires an upstream cis -acting element显示文摘	Clemens J Bulitta John V Fleming Raktima Raychowdhury Douglas Taupin Ian Rosenberg Timothy C Wang	2002	Biochemical and Biophysical Research Communications2002，，1：	1
6	Plasma vitamin E and (-carotene concertrations during radiochemotherapy preceding bone Marrow Transplantation显示文摘	Clemens MR Ladner C Ehninger G	1990	Am J Clin Nutr1990，51，2：	1
7	Self-organized nanostructures in hard ceramic coating显示文摘	Mayrhofer P H Mitterer C Clemens H	2005	Advanced Engineering Materials2005，7，12：	1
8	Greenhouse gas emissions from mechanical and biological waste treatment of municipal waste显示文摘	Clemens J Cuhls C	2003	Environ Technol2003，24，6：	1
9	Analysis of Dscam diversity in regulating axon guidance in Drosophila mushroom bodies 显示文摘	Zhan X L Clemens J C Neves G	2004	Neuron2004，43，5：	1
10	Large-scale hydrological change drove the late Miocene C4 plant expansion in the Himalayan foreland and Arabian Peninsula 显示文摘	Huang Yongsong Steven C Clemens Liu Weiguo Wang Yi Wmxen L Prell	2007	Geology2007，35，6：	1
11	Late Pleistocene variability of Arabian Sea summer monsoon winds and continental aridity: Eolian records from the lithogenic component of deep-sea sediments显示文摘	Clemens S C Prell W L	1990	Paleoceanography1990，5，：	1
12	Expression of urotensin II and its receptor in human liver cirrhosis and fulminant hepatic failure 显示文摘	LEIFELD L CLEMENS C SAUERBRUCH T	2010	Dig Dis Sci2010，55，：	1
13	Endothelial protein C receptor-dependent inhibition of human eosinophil chemotaxis by protein C显示文摘	Clemens Feistritzer Daniel H Sturn Nicole C Kaneider Angela Djanani Christian J Wiedermann	2003	The Journal of Allergy and Clinical Immunology2003，，2：	1
14	Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways显示文摘	Clemens J C Worby C A Simonson-Leff N	2000	Proceedings of the National Academy of Sciences of the United States of America2000，97，：	1
15	Crystal structures and enzymatic properties of three formyltransferases from archaea:Environmental adaptation and evolutionary relationship显示文摘	Bjorn Mamat Annette Roth Clemens Grimm C	2002	Protein Science2002，11，9：	1
16	Pentanucleotide repeat length polymorphism at the human CD4 locus显示文摘	EDWARDS M C CLEMENS P R TRISTAN M	1991	Nucleic Acids Research1991，19，17：	1
17	Vibrations of composite plate structures consisting ofa constrained-layer damping sandwich with viscoelastic core显示文摘	LU Y P CLEMENS J C ROSCOE A J	1992	Journal of Sound and vibration1992，158，3：	1
18	Two hot spots of recombi-nation in the DMD gene correlate with the deletion prone regions显示文摘	Oudet C Hanauer A Clemens Pt	1992	Hum Mol Genet1992，1，8：	1
19	The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development显示文摘	Wang Y Wan C Deng L Liu X Cao X Gilbert SR Bouxsein ML Faugere M-C Guldberg RE Gerstenfeld LC Haase VH Johnson RS Schipani E Clemens TL		0，，：	1
20	Large-scale hydrological change drove the late miocene C4 plant expansion in the Himalayan Foreland and Arabian Peninsula 显示文摘	HUANG Y S CLEMENS S C LIU W G	2007	Geology2007，35，6：	1

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