|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | One hundred and seventy-eight consecutive pancreatoduodenectomies without mortality:role of the multidisciplinary approach显示文摘BACKGROUND:Pancreatoduodenectomy offers the only chance of cure for patients with periampullary cancers.This,however,is a major undertaking in most patients and is associated with a significant morbidity and mortality.A multidisciplinary approach to the workup and follow-up of patients undergoing pancreatoduodenectomy was initiated at our institution to improve the diagnosis,resection rate,mortality and morbidity.We undertook the study to assess the effect of this approach on diagnosis,resection rates and short-term outcomes such as morbidity and mortality.METHODS:A prospective database of patients presenting with periampullary cancers to a single surgeon between April 2004 and April 2010 was reviewed.All cases were discussed at a multidisciplinary meeting comprising surgeons,gastroenterologists,radiologists,oncologists,radiation oncologists,pathologists and nursing staff.A standardized investigation and management algorithm was followed.Complications were graded according to the Clavien-Dindo classification.RESULTS:A total of 295 patients with a periampullary lesion were discussed and 178 underwent pancreatoduodenectomy (resection rate 60%).Sixty-one patients (34%) required either a vascular or an additional organ resection.Eighty-nine patients experienced complications,of which the commonest was blood transfusion (12%).Thirty-four patients (19%) had major complications,i.e.grade 3 or above.There was no in-hospital,30-day or 60-day mortality.CONCLUSIONS:Pancreatoduodenectomy can safely be performed in high-volume centers with very low mortality.The surgeon's role should be careful patient selection,intensive preoperative investigations,use of a team approach,and an unbiased discussion at a multidisciplinary meeting to optimize the outcome in these patients. | Jaswinder S Samra Raul Alvarado Bachmann Julian Choi Anthony Gill Michael Neale Vikram Puttaswamy Cameron Bell Ian Norton Sarah Cho Steven Blome Ritchie Maher Sivakumar Gananadha Thomas J Hugh | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，4： | 8 |
| 2 | Features of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma显示文摘BACKGROUND Extrahepatic metastasis(EHM)of hepatocellular carcinoma(HCC)is associated with poor outcomes.However,the clinical features and risk factors of EHM of HCC after radiofrequency ablation(RFA)remain unclear.AIM To elucidate the characteristics and risk factors of EHM after RFA for HCC.METHODS From January 2008 to December 2017,we retrospectively enrolled 661 patients who underwent RFA as first-line treatment for HCC at 2 tertiary hospitals.The inclusion criteria were age≥18 years,a diagnosis of HCC,and treatment-naivety.Abdominal computed tomography(CT)or magnetic resonance imaging(MRI)and alpha-fetoprotein measurements were routinely performed at 1 mo after RFA and followed-up at intervals of 3-6 mo.Univariate analyses were performed using the chi-squared test or Student’s t-test,and univariate and multivariate analyses were performed via logistic regression,as appropriate.RESULTS EHM was diagnosed in 44 patients(6.7%)during a median follow-up period of 1204 days.The 10-year cumulative rate of HCC recurrence and EHM was 92.7%and 33.7%,respectively.Initial recurrence was most often intrahepatic,and the rate of extrahepatic recurrence at initial recurrence was only 1.2%.The median time to the diagnosis of EHM was 2.68 years,and 68.2%of patients developed EHM within 2 years of the first recurrence,regardless of recurrence-free survival and 75.0%of patients developed EHM within 5 years after first recurrence.EHM was mostly diagnosed via abdominal CT/MRI in 33(75.0%)and 38 of 44 patients(86.4%)with EHM had either positive abdominal CT scan results or serum AFP level elevation.In multivariate analysis,recurrence-free survival<2 years,ablation zone/tumor size<2,and alpha-fetoprotein level>400 IU/mL were associated with a high EHM risk.CONCLUSION EHM occurs following multiple intrahepatic recurrences after RFA and combined contrast-enhanced abdominal CT and serum AFP were useful for surveillance.Patients especially with high-risk factors require close follow-up for EHM. | Jae H Yoon Young J Goo Chae-Jun Lim Sung K Choi Sung B Cho Sang S Shin Chung H Jun | 2020 | World Journal of Gastroenterology2020，26，32： | 3 |
| 3 | Generalized set-valued variational inclusions in Banach spaces 显示文摘 | Chang S S Cho Y J Lee B S | 2000 | J Math Anal Appl2000，246，： | 2 |
| 4 | Enhanced cellular immunity to hepatitis C virus nonstructural proteins by codelivery of granulocyte macrophage-colony stimulating fact or gene in intramuscular DNA immunization显示文摘 | Cho J H Lee S W Sung Y C | 1999 | Vaccine1999，17，910： | 2 |
| 5 | Optimal induction of hepatitis C virus envelope-specific immunity by bicistronic plasmid DNA inoculation with the granulocyte-macrophage-colony stimulating factor gene显示文摘 | Lee S W Cho J H Sung Y C | 1998 | J Virol1998，72，10： | 2 |
| 6 | Damage identification in beam-type structures: frequency-based method vs mode-shape-based method 显示文摘 | Kim J T Ryu Y S Cho H M | 2003 | Engineering Structures2003，25，1： | 2 |
| 7 | A study of magnetic and optical properties of Cu-doped ZnO 显示文摘 | LEE H J KIM B S CHO C R | 2004 | Phys Status Solidi B2004，241，7： | 1 |
| 8 | Dispersion polymerization of acrylamide with quaternary ammonium cationic comonomer in aqueous solution显示文摘 | Song B K Cho M S Yoon K J | 2003 | J Appl Polym Sci2003，87，： | 1 |
| 9 | An anti-apoptotic protein human survivin is a direct inhibitor of Caspase-3 and-7显示文摘 | Sung B J Cho YS Kim H J Ha NC Hwang JI | 2001 | Biochenistry2001，40，4： | 1 |
| 10 | Chaos and control of discrete dynamic traffic model显示文摘 | Lo S C Cho H J | 2005 | Journal of the Franklin Institute2005，342，7： | 1 |
| 11 | Clinical outcomes of metastatic breast cancer patients with triple-negative phenotype who received platinumcontaining chemotherapy显示文摘 | Yi S Uhm J Cho E | 2008 | J Clin Oncol2008，26，15： | 1 |
| 12 | Properties of dynamically vulcanized EPDM and LLDPE blends显示文摘 | Kim K H Cho W J Ha C S | 1996 | J Appl Polym Sci1996，59，2： | 1 |
| 13 | A fieldemission display with a selffocus cathode electrode显示文摘 | Choi Y S Cho Y S Kang J H | 2003 | Appl Phys Lett2003，82，20： | 1 |
| 14 | The placebo response in the treatment of chronic fatigue syndrome: a systematic review and meta-analysis 显示文摘 | Cho H J Hotopf M Wessely S | 2005 | Psychosom Med2005，67，2： | 1 |
| 15 | Raman spectroscopic evaluation of polyacrylonitrile - based carbon nanofibers prepared by electrospinning 显示文摘 | Kim C Park S H Cho J I | 2004 | Journal of Raman Spectroscopy2004，35，11： | 1 |
| 16 | Thermoelastic analysis of kick motor nozzle incorporating spatially reinforced composites 显示文摘 | Yoo J S Cho I Kim C G | 2003 | Journal of Spacecraft and Rockets2003，40，1： | 1 |
| 17 | Colorectal canc-er cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endo-thelial cells显示文摘 | HONG B S CHO J H KIM H | 2009 | BMC Genomics2009，10，： | 1 |
| 18 | Investigation into the effects of mosapride on motility of Guinea pig stomach, ileum, and colon显示文摘 | Ji S W Park H J Cho J S | 2003 | Yonsei Med J2003，44，4： | 1 |
| 19 | Microencapsulation of octadecane as a phase-change material by interfacial polymerization in an emulsion system 显示文摘 | Cho J S Kwon A Cho C G | 2002 | Collid Polym Sci2002，280，： | 1 |
| 20 | Identification and classification of S haplotypes in Raphanus sativus by PCR-RFLP of the S locus glycoprotein (SLG) gene and the S locus receptor kinase (SRK) gene显示文摘 | Lim S H Cho H J Lee S J Hiderki M | 2002 | Plant Cell2002，104，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员