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| 1 | Coarctation of the aorta:Management from infancy to adulthood显示文摘Coarctation of the aorta is a relatively common form of congenital heart disease, with an estimated incidence of approximately 3 cases per 10000 births. Coarctation is a heterogeneous lesion which may present across all age ranges, with varying clinical symptoms, in isolation, or in association with other cardiac defects. The first surgical repair of aortic coarctation was described in 1944, and since that time, several other surgical techniques have been developed and modified. Additionally, transcatheter balloon angioplasty and endovascular stent placement offer less invasive approaches for the treatment of coarctation of the aorta for some patients. While overall morbidity and mortality rates are low for patients undergoing intervention for coarctation, both surgical and transcatheter interventions are not free from adverse outcomes. Therefore, patients must be followed closely over their lifetime for complications such as recoarctation, aortic aneurysm, persistent hypertension, and changes in any associated cardiac defects. Considerable effort has been expended investigating the utility and outcomes of various treatment approaches for aortic coarctation, which are heavily influenced by a patient's anatomy, size, age, and clinical course. Here we review indications for intervention, describe and compare surgical and transcatheter techniques for management of coarctation, and explore the associated outcomes in both children and adults. | Rachel D Torok Michael J Campbell Gregory A Fleming Kevin D Hill | 2015 | World Journal of Cardiology2015，7，11： | 27 |
| 2 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 3 | Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders显示文摘 | E Joanna Baxter Linda M Scott Peter J Campbell Clare East Nasios Fourouclas Soheila Swanton George S Vassiliou Anthony J Bench Elaine M Boyd Natasha Curtin Mike A Scott Wendy N Erber Anthony R Green | 2005 | The Lancet . 2005 (9464)2005，，： | 2 |
| 4 | Influence of birth order, birth weight, colostrum and serum immunoglobulin G on neonatal piglet survival显示文摘Background: Intake of colostrum after birth is essential to stimulate intestinal growth and function, and to provide systemic immunological protection via absorption of Immunoglobulin G (IgG). The birth order and weight of 745 piglets (from 75 litters) were recorded during a one-week period of farrowing. Only pigs weighing greater than 0.68 kg birth weight were chosen for the trial. Sow colostrum was collected during parturition, and piglets were bled between 48 and 72 hours post-birth. Piglet serum IgG and colostral IgG concentrations were determined by radial immunodiffusion. Results: Sow parity had a significant (P < 0.001) effect on sow colostral IgG concentration, being 5% higher in multiparous females. Sow colostral IgG concentration explained 6% and piglet birth order accounted for another 4% of the variation observed in piglet serum IgG concentration (P < 0.05); however, birth weight had no detectable effect. Piglet serum IgG concentration had both a linear (P < 0.05) and quadratic effect (P < 0.05) on % survival. Piglets with 1,000 mg/dl serum IgG or less (n=24) had a 67% survival; whereas, piglets with IgG concentrations between 2250 to 2500 mg/dl (n=247) had a 91% survival. Birth order had no detectable effect on survival, but birth weight had a positive linear effect (P < 0.05). Piglets weighing 0.9 kg (n = 107) at birth had a 68% survival rate, and those weighing 1.6 kg (n = 158) had an 89% survival. Conclusion: We found that the combination of sow colostrum IgG concentration and birth order can account for 10% of the variation of piglet serum IgG concentration and that piglets with less than 1,000 mg/dl IgG serum concentration and weight of 0.9 kg at birth had low survival rate when compared to their larger siblings. The effective management of colostrum uptake in neonatal piglets in the first 24 hrs post-birth may potentially improve survival from birth to weaning. | Rafael A Cabrera Xi Lin Joy M Campbell Adam J Moeser Jack Odle | 2013 | Journal of Animal Science and Biotechnology2013，4，2： | 2 |
| 5 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013，19，21： | 2 |
| 6 | The role of chemokine in the microenvironmental control of T versus B cell arrest in Peyer's patch high endothelial venules 显示文摘 | Warnock R A Campbell J J Drof M E | 2000 | J Exp Med2000，191，： | 2 |
| 7 | Mechanisms of Disease: the Myeloprolife Rative Disorders显示文摘 | Campbell P J Green A R | 2006 | N Engl J Med2006，355，： | 1 |
| 8 | Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities显示文摘 | SANYAL A J CAMPBELL SARGENT C MIRSHAHI F | 2001 | Gastroenterology2001，120，5： | 1 |
| 9 | Investigation into refractories as crucible and mould materials for melting and casting γ-TiAl alloys 显示文摘 | KUANG J P HARDING R A CAMPBELL J | 2000 | Mater Sci Technol2000，16，9： | 1 |
| 10 | Mapping components of flour and noodle color in Australian wheat显示文摘 | Mares D J Campbell A W | 2001 | Australian Journal of Agricultural Research2001，52，： | 1 |
| 11 | The phosphatidylinositol3'-kinase p85 alpha gene is an oncogene in human ovarian and colon tumors显示文摘 | Philp A J Campbell IG Leet C | 2001 | Cancer Res2001，61，20： | 1 |
| 12 | Detecting and reducing hospital adverse events : outcomes of the wimmera clinical risk management program显示文摘 | Wolf A Bourke J Campbell I | 2001 | MJA2001，174，： | 1 |
| 13 | Rhenium behavior in molybdenite in hypogene and near surface environments : Implications for Re-Os geochronometry 显示文摘 | McCandless T E Ruiz J Campbell A R | 1993 | Geochimica et Cosmochimica Acta1993，57，： | 1 |
| 14 | Competitive interactions between endogenous LTD and LTP in the hippoeampus underlie the storage of emo- tional memories and stress-induced amnesia 显示文摘 | Diamond D M Park C R Campbell A M Woodson J C | 2005 | Hip- pocampus2005，15，： | 1 |
| 15 | Maternal concern and perceptions of overweight in Australian preschoolaged children显示文摘 | Campbell MW Williams J Hampton A | | 0，，06： | 1 |
| 16 | Evidence of the downward-propagating annual wind reversal in the equatorial stratosphere显示文摘 | REED R J CAMPBELL W J RASMUSSEN L A | | 0，，03： | 1 |
| 17 | Analytics in higher education: Establishing a common language 显示文摘 | VAN BARNEVELD A ARNOLD K E CAMPBELL J P | 2012 | EDU- CAUSE Learning Initiative2012，，： | 1 |
| 18 | Comparison of regression coefficient and GIS-based methodologies for regional estimates of forest soil carbon stocks显示文摘 | CAMPBELL J E MOEN J C RICHHARD A N | 2008 | Environ Pollut2008，152，： | 1 |
| 19 | Seismic Monitoring and Verification for the CO2CRC Otway Basin Project, Part 2: acquisition and analysis of borehole seismic data 显示文摘 | Urosevic F Campbell A J Dahlhaus L | 2009 | Energy Procedia2009，1，1： | 1 |
| 20 | What Moves Housing Markets: A Variance Decomposi- tion of the Rent Price Ratio 显示文摘 | CAMPBELL S D DAVIS M A GALLIN J and MARTIN R F | 2009 | Journal of Urban Econom- ics2009，66，： | 1 |
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