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41篇 您的检索式：作者名="Burkholder S"

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	题名	作者	年代	出处	被引量
1	Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.	Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel	2014	World Journal of Gastroenterology2014，20，42：	5
2	Colorectal carcinomas with high microsatellite instability:defining a distinct immunologic and molecular entity with respect to prognostic markers显示文摘	Edmonston T B Cuesta K H Burkholder S		0，，：	1
3	Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer显示文摘	Watkins D N Berman D M Burkholder S G	2003	Nature2003，422，6929：	1
4	Relationship between muscle fiber types and sizes and muscle architectural properties in the mouse hindlimb显示文摘	Burkholder TJ Fingado B Baron S	1944	Morphol1944，221，2：	1
5	Ozone depletion and global warming potentials of CFsI显示文摘	Solomon S Burkholder J B Ravishankara A	1994	Journal of Geophysical Research1994，99，20：	1
6	In vivo and in vitro gene transfer to mammalians omatic cells by particle bom bardment显示文摘	Yang N S Burkholder J	1990	Proc Natl Acad Sci USA1990，87，：	1
7	Analysis of a full spectrum hybrid lighting system 显示文摘	Schlegel G O Burkholder F W Klein S A	2004	Solar Energy2004，76，4：	1
8	Analysis of a full spectrum hybrid lighting system 显示文摘	Schlegel G O Burkholder F W Klein S A	2004	Solar Energy2004，76，4：	1
9	Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer显示文摘	Watkins D N Berman D M Burkholder S G	2003	Nature2003，422，6929：	1
10	Effect ofsublethal heat stress on Salmonella Typhimurium virulence显示文摘	SIRSAT S A BURKHOLDER K M MUTHAIYAN A	2011	J ApplMicrobiol2011，110，3：	1
11	Interactions between the toxic estuarine dinoflagellate Pfiesteria piscicida and two species of bivalve molluscs显示文摘	Springer J J Shumway S E Burkholder J A M	2002	Mar Ecol Prog Ser2002，245，：	1
12	Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer显示文摘	Watkins D N Berman D M Burkholder S G	2003	Nature2003，422，6929：	1
13	Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer 显示文摘	Watkins D N Berman D M Burkholder S G	2003	Nature2003，422，6929：	1
14	Photochemistry of acetone under tropospheric conditions显示文摘	GIERCZAK T BURKHOLDER J B BAUERLE S	1998	Chem Phys1998，231，23：	1
15	Video assisted transumhilical appendectomy in children 显示文摘	Koontz C S Smith L A Burkholder H C	2006	Pediatr Surg2006，41，4：	1
16	Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer显示文摘	WATKINS D N BERMAN D BURKHOLDER S G	2003	Nature2003，422，6929：	1
17	On the ozone depletion and global warming potential of CH31 显示文摘	Solomon S Burkholder J B Ravishankara A R	1994	Journal of Geophysical Research1994，99，20：	1
18	Human wrist motor biomechanical design and application to tendon transfers显示文摘	Loren G J Shoemaker S D Burkholder T J	1996	J Biomechanics1996，29，3：	1
19	Solid state coordination chemistry of oxomolybdenum organoarsonate materials 显示文摘	BURKHOLDER E WRIGHT S GOLUB V	2003	InorgChem2003，42，23：	1
20	Ozone depletion and global warming potentials of CF31显示文摘	Solomon S Burkholder J B Ravishankara A R	1999	Journal of Geophysical Re- search: Atmospheres 0984-2012)1999，，20：	1

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