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| 1 | 虚拟现实技术应用于神经心理评估的研究概述显示文摘传统神经心理评估的实验控制和生态效度的平衡问题日益受到研究人员的关注,而新兴的虚拟现实(Virtual Reality,VR)技术为问题的改善带来了希望,它不仅可以模拟现实环境并支持被试的直接交互,而且能对传统测试进行再现和扩展。它所形成的评估系统能对刺激的内容和表象、任务的复杂度和被试的响应进行灵活控制,所获取的信息更丰富、准确。在初步评估注意过程(注意、单侧空间忽略)、记忆(前瞻记忆、情景记忆、空间记忆、地形定向)和执行功能方面已获得了令人满意的效果。然而目前VR评估的应用仍存在技术和设备方面的不足,以及对评估者和被试不同操作要求的局限,因此今后除了要规范化现有VR评估系统,还应该进一步发展基础条件来推动系统的广泛应用。 | 郑霞 SAUZEON Helene 周明全 N'KAOUA Bernard | 2010 | 心理科学进展2010,18,3: | 11 |
| 2 | Immuno-haematologic and virologic responses and predictors of virologic failure in HIV-1 infected adults on first-line antiretroviral therapy in Cameroon显示文摘Background:Contemporary data on the immunologic,haematologic and virologic responses and predictors of virologic failure after initiation of free antiretroviral treatment in Cameroon are needed to evaluate the current treatment-monitoring algorithm and to complement efforts to scale-up and improve on the management of HIV infections.Methods:This was a cross-sectional study conducted between October 2010 and June 2012.A total of 951 participants aged 18-74 years were recruited from selected approved HIV treatment centres of the Northwest and Southwest regions.This comprised 247 males and 704 females.Demographic,self-reported risk behaviours and socioeconomic data were obtained using a structured questionnaire.Full blood and CD4+T-cell counts were done using standard automated techniques.Determination of viral load(VL)was done using Abbott RealTime HIV-1 m2000™system.Data was analysed using SPSS version 17.The statistical significance level was P<0.05.Results:The median duration of antiretroviral therapy(ART)was 24 months.The population mean CD4+T-cell count was 255.3 cells/μL[95%CI,236.8-273.9].Overall,45.9%,43.8%and 10.2%of the participants had CD4+T-cell counts of<200 cells/μL,200-499 cells/μL and>500 cells/μL respectively.Anaemia was present in 26.2%of the participants with 62.3%,25.7%and 12%described as mild,moderate and severe anaemia respectively.Virologic failure occurred in 23.2%of the participants with 12.3%having VL>10,000 RNA copies/mL.Meanwhile 76.8%of patients attained adequate viral suppression with 40.8%having undetectable viral load.The age group 18-29 years(p=0.024),co-infection with tuberculosis(p=0.014),anaemia(p=0.028)and distance from the treatment centre(p=0.011)independently predicted virologic failure.Conclusion:The majority of the participants achieved adequate viral suppression after≥6 months of ART.Despite these favourable immuno-haematologic and virologic outcomes,the National AIDS Control Program should step-up efforts to improve on antiretroviral drug distribution,as well as proper assessment and management of anaemia,foster early diagnosis and treatment of tuberculosis and enhance treatment adherence counselling especially in younger patients. | Henry D Meriki Kukwah A Tufon Mbunkah H Afegenwi Bernard A Nyindem Pascal N Atanga Damian N Anong Fidelis Cho-Ngwa Theresa Nkuo-Akenji | 2014 | Infectious Diseases of Poverty2014,3,1: | 3 |
| 3 | Heavy metal removal from sediments by biosurfactants显示文摘 | Catherine N Mulligan Raymond N Yong Bernard F Gibbs | 2001 | Journal of Hazardous Materials2001,,1: | 2 |
| 4 | Evaluation of ethnobotanically selected Benin medicinal plants for their in vitro antiplasmodial activity显示文摘 | Bernard Weniger Latifou Lagnika Catherine Vonthron-Sénécheau Tomabu Adjobimey Joachim Gbenou Mansourou Moudachirou Reto Brun Robert Anton Ambaliou Sanni | 2003 | Journal of Ethnopharmacology2003,,2: | 2 |
| 5 | Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study显示文摘 | Andri Rauch Zoltán Kutalik Patrick Descombes Tao Cai Julia Di Iulio Tobias Mueller Murielle Bochud Manuel Battegay Enos Bernasconi Jan Borovicka Sara Colombo Andreas Cerny Jean–Fran?ois Dufour Hansjakob Furrer Huldrych F. Günthard Markus Heim Bernard Hirs | 2010 | Gastroenterology2010,,4: | 2 |
| 6 | B - myb rescues ras - induced premature senescence, which requires its transactivation domain 显示文摘 | Masselink H Vastenhouw N Bernards R | 2001 | Cancer Lett2001,171,1: | 1 |
| 7 | Reevaluation of formulas for predicting creatinine clearance in adults and children,using compensated creatinine methods显示文摘 | Wuyts B Bernard D Van den Noortgate N | 2003 | Clin Chem2003,49,61: | 1 |
| 8 | Image segmentation by a contrario simulation显示文摘 | Burrus N Bernard T Jolion J | 2009 | Pattern Recognition2009,42,7: | 1 |
| 9 | Condensation of gly-oxal with triethylenetetraamine:Stereochemistry,cyclizationand deprotection 显示文摘 | Herve G Bernard H Le Bris N | 1999 | Tetrahedron Letters*1999,40,13: | 1 |
| 10 | Continuation of pregnancy after first-trimester exposure to mifepristone:an observational prospective study显示文摘 | Bernard N Elefant E Carlier P | 2013 | BJOG2013,120,5: | 1 |
| 11 | Characterization of the chicken serotonin N-acetyltransferase gene-Activation via clock gene heterodimer/E box interaction显示文摘 | Chong N W Bernard M Klein D C | 2000 | J Biol Chem2000,275,32: | 1 |
| 12 | Comparison of gene expression profiles in human keratinocyte mono-layer cultures, reconstituted epidermis and normal human skin; transcriptional effects of retinoid treatments in reconstituted human epidermis 显示文摘 | Bernard FX Pedretti N Rosdy M | 2002 | Exp Dermatol2002,11,: | 1 |
| 13 | The influence of the pretrestment of powder on the resulting properties of LaNi5 electrodes显示文摘 | Boonstra A H Bernards T M N | 1990 | J Less Common Metals1990,161,2: | 1 |
| 14 | Thermal management and resistive rail heating of a large-scale naval electromagnetic launcher显示文摘 | Smith A N Ellis R L Bernarde J S | 2005 | IEEE Trans on Magn2005,41,1: | 1 |
| 15 | Minimizing the risk of reporting false positives in large-scale RNAi screens显示文摘 | Echeverri C.J Beachy P.A Baum B Boutros M Buchholz F Chanda K K Downward J Ellenberg J Fraser A.G Hacohen N Hahn W.C Jackson A.L Kiger A Linsley P.S Lum L Ma Y Mathey-Prevot B Root D.E Sabatini D.M Taipale J Perrimon N and Bernards R | | 0,,: | 1 |
| 16 | Psychological correlates of depression in fathers and mothers in the first postnatal year显示文摘 | Dudley M Kelk N Bernard D | 2001 | J Reprod Infant Psychol2001,19,3: | 1 |
| 17 | Procaleitonin as a diagnostic tetct for sepsis in critically ill adults and after surgery or trauma:a systematic review and mets-analysis显示文摘 | Bernard U Regis C Patrick N | | 0,,07: | 1 |
| 18 | Structure and size of bronchopulmonary anastomoses in sheep lung显示文摘 | Bernard S Luchtel D L Polissar N | 2005 | Anat Rec2005,286,1: | 1 |
| 19 | Phosphorus losses in irrigation runoff from fertilized pasture显示文摘 | Austin N R Bernard P J Collins M D | 1996 | Journal of Environmental Quality1996,25,: | 1 |
| 20 | Elaborated modeling and control for autonomous small size helicopters显示文摘 | Kondak K Bernard M Losse N | 2006 | VDI Berichte2006,1956,: | 1 |