|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Bone mineral density and disorders of mineral metabolism in chronic liver disease显示文摘AIM:To estimate the prevalence and identify the risk factors for metabolic bone disease in patients with cirrhosis.METHODS:The study was performed on 72 Indian patients with cirrhosis(63 male, 9 female;aged < 50 years).Etiology of cirrhosis was alcoholism(n = 37), hepatitis B(n = 25) and hepatitis C(n = 10).Twenty-three patients belonged to Child class A, while 39 were in class B and 10 in class C.Secondary causes for metabolic bone disease and osteoporosis were ruled out.Sunlight exposure, physical activity and dietary constituents were calculated.Complete metabolic profiles were derived, and bone mineral density(BMD) was measured using dual energy X ray absorptiometry.Low BMD was defined as a Z score below-2.RESULTS:Low BMD was found in 68% of patients.Lumbar spine was the most frequently and severely affected site.Risk factors for low BMD included low physical activity, decreased sunlight exposure, and low lean body mass.Calcium intake was adequate, with unfavorable calcium:protein ratio and calcium:phosphorus ratio.Vitamin D deficiency was highly prevalent(92%).There was a high incidence of hypogonadism(41%).Serum estradiol level was elevated significantly in patients with normal BMD.Insulin-like growth factor(IGF) 1 and IGF binding protein 3 levels were below the age-related normal range in both groups.IGF-1 was signiflcantly lower in patients with low BMD.Serum osteocalcin level was low(68%) and urinary deoxypyridinoline to creatinine ratio was high(79%), which demonstrated low bone formation with high resorption.CONCLUSION:Patients with cirrhosis have low BMD.Contributory factors are reduced physical activity, low lean body mass, vitamin D def iciency and hypogonadism and low IGF-1 level. | Joe George Hosahithlu K Ganesh Shrikrishna Acharya Tushar R Bandgar Vyankatesh Shivane Anjana Karvat Shobna J Bhatia Samir Shah Padmavathy S Menon Nalini Shah | 2009 | World Journal of Gastroenterology2009，15，28： | 15 |
| 2 | Relationship between HER-2 overexpression and brain metastasis in esophageal cancer patients显示文摘AIM:To study if HER-2 overexpression by locally advanced esophageal cancers increase the chance of brain metastasis following esophagectomy.METHODS:We retrospectively reviewed the medical records of esophageal cancer patients who underwent esophagectomy at University of Iowa Hospitals and Clinics between 2000 and 2010.Data analyzed consisted of demographic and clinical variables.The brain metastasis tissue was assayed for HER-2 overexpression utilizing the FDA approved DAKO Hercept Test.RESULTS:One hundred and forty two patients were reviewed.Median age was 64 years(36-86 years).Eighty eight patients(62%) received neoadjuvant chemoradiotherapy.Pathological complete and partial responses were achieved in 17(19%) and 71(81%) patients.Cancer relapsed in 43/142(30%) patients.The brain was the first site of relapse in 9/43 patients(21%,95% CI:10%-36%).HER-2 immunohistochemistry testing of the brain metastasis tissue showed that 5/9(56%) cases overexpressed HER-2(3+ staining).CONCLUSION:HER-2 overexpression might be associated with increased risk of brain metastasis in esophageal cancer patients following esophagectomy.Further studies will be required to validate this observation. | Taher Abu Hejleh Barry R DeYoung Eric Engelman Jeremy M Deutsch Bridget Zimmerman Thorvardur R Halfdanarson Daniel J Berg Kalpaj R Parekh William R Lynch Mark D Iannettoni Sudershan Bhatia Gerald Clamon | 2012 | World Journal of Gastrointestinal Oncology2012，4，5： | 5 |
| 3 | Factors involved in immunity against Actinobacillus pleuropneumoniae 显示文摘 | Bhatia B Mittal K R Frey J | 1991 | Vet Microbiol1991，29，： | 2 |
| 4 | Factors involved in immunity a- gainst Actinobacillus pleuropneumoniae in mice显示文摘 | Bhatia B Mittal K R Frey J | 1991 | Vet Microbi- ol1991，29，2： | 1 |
| 5 | The effectiveness of a levonorgestrel-releasing intrauterine system (LNG- IUS) in the treatment of endometrial hyperplasia - a long - term follow - up study 显示文摘 | Varma R Soneja H Bhatia K | 2008 | Eur J Obstet Gynecol Reprod Biol2008，139，2： | 1 |
| 6 | Efficacy of less invasive posterior lumbar interbody fusion as revision surgery forpatients with recurrent symptoms after discectomy 显示文摘 | Lakkol S Bhatia C Taranu R | 2011 | J Bone Joint Surg(Br)2011，93，11： | 1 |
| 7 | Immunoglobulin G and complement C3 levels in pregnancy induced hypertension显示文摘 | Ramdenee G R Matah M Bhatia B D | 1996 | Indian Pediatr1996，32，2： | 1 |
| 8 | Prophylactic dexam-ethasone for postoperative nausea and vomiting in pediatric strabis-mus surgery : a dose ranging and safety evaluation study 显示文摘 | Madan R Bhatia A Chakithandy S | 2005 | Anesth Analg2005，100，： | 1 |
| 9 | Modification of coal tar pitch by chemical method to reduce benzo(a)pyrene显示文摘 | Kaushi S Raina R K Bhatia G | 2007 | Current Science2007，93，： | 1 |
| 10 | Com- patibility of biodegradable poly ( lactic acid ) ( PLA ) and poly( butylene succinate) (PBS) blends for packaging ap- plication 显示文摘 | BHATIA A GUPTA R BHATrACHARYA S | 2007 | Korean-Aust Rheology J2007，19，3： | 1 |
| 11 | A Cauchy-Schwarz inequality for operators with applications显示文摘 | Bhatia R and Davis C | 1995 | Linear Algebra Appl1995，223，： | 1 |
| 12 | Factors involved in immunity against Actionbacillus pleuropmeumonia in mice 显示文摘 | Bhatia B Mittal K R Frey J | 1991 | Vet Microbiol1991，29，： | 1 |
| 13 | Keratomalacia in a neonate secondary to maternal vitamin A deficiency显示文摘 | Gupta M Jora R Bhatia R | 2005 | Indian J Pedi-art2005，72，10： | 1 |
| 14 | Oxygen separation from air using ceramic-based membrane technology for sustainable fuel production and power generation 显示文摘 | Hashim S S Mohamed A R Bhatia S | 2011 | Renewable and Sustainable Energy Reviews2011，15，2： | 1 |
| 15 | Trace element characteristics of greywackes and tectonic setting discrimination of sedimentary basins显示文摘 | BHATIA M R and CROOK K A W | 1986 | Contrib Mineral Petrol1986，92，： | 1 |
| 16 | Trace element characteristics of grey- wacke and tectonic setting discrimination of sedimentary basins 显示文摘 | Bhatia M R Crook K A W | 1986 | Contributions to Mineralogy and Petrology1986，92，2： | 1 |
| 17 | Research in particle coating and agglomeration at West Virginia 显示文摘 | TURTON R BHATIA A HAKIM H | 2001 | Powder Tec hnnlogy2001，117，： | 1 |
| 18 | Bioenergetic cost of heat tolerance in wheatcrop 显示文摘 | Mitra R Bhatia C R | 2008 | Current Science2008，94，8： | 1 |
| 19 | Rank university websites using fuzzy AHP and fuzzy TOPSIS approach on usability显示文摘 | NAGPAL R MEHROTRA D BHATIA P K | 2015 | International journal of information engineering and electronic business2015，，1： | 1 |
| 20 | Structural investigation of the saponified products of acrylonitrile terpolymer by PMR and CMR spectroscogy显示文摘 | Bhatia M Bajaj P Chavan R B | 1987 | Fair Polym J1987，23，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员