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| 1 | Embolization of splenorenal shunt associated to portal vein thrombosis and hepatic encephalopathy显示文摘Hepatic encephalopathy(HE)is a cognitive disturbance characterized by neuropsychiatric alterations.It occurs in acute and chronic hepatic disease and also in patients with portosystemic shunts.The presence of these portosystemic shunts allows the passage of nitrogenous substances from the intestines through systemic veins without liver depuration.Therefore,the embolization of these shunts has been performed tocontrol HE manifestations,but the presence of portal vein thrombosis is considered a contraindication.In this presentation we show a cirrhotic patient with severe HE and portal vein thrombosis who was submitted to embolization of a large portosystemic shunt.Case report:a 57 years-old cirrhotic patient who had been hospitalized many times for persistent HE and hepatic coma,even without precipitant factors.She had a wide portosystemic shunt and also portal vein thrombosis.The abdominal angiography confirmed the splenorenal shunt and showed other shunts.The larger shunt was embolized through placement of microcoils,and the patient had no recurrence of overt HE.There was a little increase of esophageal and gastric varices,but no endoscopic treatment was needed.Since portosystemic shunts are frequent causes of recurrent HE in cirrhotic patients,portal vein thrombosis should be considered a relative contraindication to perform a shunt embolization.However,in particular cases with many shunts and severe HE,we found that one of these shunts can be safely embolized and this procedure can be sufficient to obtain a good HE recovery.In conclusion,we reported a case of persistent HE due to a wide portosystemic shunt associated with portal vein thrombosis.As the patient had other shunts,she was successfully treated by embolization of the larger shunt. | Letícia de Campos Franzoni Fábio Cardoso de Carvalho Rafael Gomes de Almeida Garzon Fábio da Silva Yamashiro Laís Augusti Lívia Alves Amaral Santos Mariana de Souza Dorna Júlio Pinheiro Baima Talles Bazeia Lima Carlos Antonio Caramori Giovanni Faria Silva Fernando Gomes Romeiro | 2014 | World Journal of Gastroenterology2014，20，42： | 6 |
| 2 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 3 | 年龄≥65岁男性收缩压与血管疾病的相关性显示文摘老年人血压与血管疾病的关系尚不确定。1996-1999年,在澳大利亚西部帕斯普通人群中建立65~94岁男性7564人的前瞻性队列,评估收缩压与主要血管事件的相关性。测定基线和2001-2004年再调查时的收缩压。记录受试者的致命性及非致命性血管事件。 | Lacey B Golledge J Yeap BB Lewington S McCaul KA Norman PE Flicker L Almeida OP Hankey GJ 赵狄 练桂丽 | 2017 | 中华高血压杂志2017，25，5： | 2 |
| 4 | Preparation of conducting polyanilines doped with Keggin - type polyoxometalates and their application as counter electrode in dye - sensitized solar cells显示文摘 | ALMEIDA L GONCALVES A BENEDETTI J MIRANDA P PASSONI L NOGUEIRA A | 2010 | J Mater Sci2010，45，18： | 1 |
| 5 | Improving hierarchical cluster analysis: a new method with outlier detection and automatic clustering显示文摘 | ALMEIDA J A S BARBOSA L M S PAIS A A C C | 2007 | Chemometrics and Intelligent Labora- tory Systems2007，87，2： | 1 |
| 6 | Genetic dissection of vitamin E biosynthesis in tomato 显示文摘 | Almeida J Quadrana L Asis R | 2011 | J Experimental Botany2011，62，： | 1 |
| 7 | A mul- tiobjective modeling approach to locating incinerators 显示文摘 | Alada - Almeida L Coutinho - Rodrigues J Current J | 2009 | Socio -Economic Planning Sciences2009，，2： | 1 |
| 8 | Linear alkybenzene显示文摘 | De Almeida J L G Dufaux M Taarit Y B | 1994 | JAOCS1994，71，7： | 1 |
| 9 | Effectsof glycosylation on heparin binding and antithromhin activation by hep-arin显示文摘 | Pol-Fachin L Franco Becker C Almeida Guimaraes J | 2011 | Proteins2011，79，9： | 1 |
| 10 | Endocrinological and catecholaminergic alterations during sleep deprivation and recovery in male rats显示文摘 | Andersen M L Martins P J D 'Almeida V | 2005 | J Sleep Res2005，14，1： | 1 |
| 11 | Role of DIVARICATA in the control of dorsoventral asymmetry in Antirrhinum flowers 显示文摘 | GALEGO L Almeida J | 2002 | Genes Dev2002，16，： | 1 |
| 12 | Summary cache: a scalable wide-area Web cache sharing protocol显示文摘 | FAN L CAO P ALMEIDA J BRODER A Z | 2000 | IEEE-ACM Trans on Networking2000，8，3： | 1 |
| 13 | Determination of E-2-nonenal by high-performance liquid chromatography with UV detection assay for the evaluation of beer ageing显示文摘 | Santos J R Carneiro J R Guido L F Almeida P J Rodrigues J A Barros A A | 2003 | J Chromatog A2003，985，12： | 1 |
| 14 | A new D-type cyclin of Arabidopsis thaliana expressed during lateral root primor- dia formation 显示文摘 | VEYLDER L ALMEIDA E J BURSSENS S | 1999 | Planta1999，208，4： | 1 |
| 15 | Age-related effects of dexamethasone administration in adrenal zona reticularis显示文摘 | Almeida H Matos L Ferreira J | 2006 | Ann N Y Acad Sci2006，1067，： | 1 |
| 16 | Impro- ving power system dynamic behavior through doubly fed induction machines controlled by static converter using fuzzy control 显示文摘 | G De Almeida Rogerio J A Pecas Lopes J A L Barreiros | 2004 | IEEE Transaction on Power System November2004，19，4： | 1 |
| 17 | Porcine circovirus 2 (PCV2) induces a procoagulant state in naturally infected swine and in cultured endothelial cells显示文摘 | Marks F S Reck J Jr Almeida L L | 2009 | Vet Microbiol2009，143，： | 1 |
| 18 | Suppression of strain-induced cross-hatch on molecular beam epitaxy (211)B HgCdTe 显示文摘 | M Martinka L A Almeida J D Benson | 2002 | Journal of Electronic Materials2002，31，7： | 1 |
| 19 | The FTT-CAN protocol: why and how 显示文摘 | Almeida L Pedreiras P Alberto J G | 2002 | IEEE Transactions on Industrial Electronics2002，49，6： | 1 |
| 20 | Improving hierarchical cluster analysis: A new method with outlier detection and automatic clustering显示文摘 | ALMEIDA J A S BARBOSA L M S PAIS A A C C | 2007 | Chemometrics and Intelligent Laboratory Systems2007，87，： | 1 |
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