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154篇 您的检索式:作者名="ANN S J"
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1Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels 2010World Journal of Gastroenterology2010,16,6:11
2Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor显示文摘Anne Brunet Azad Bonni Michael J Zigmond Michael Z Lin Peter Juo Linda S Hu Michael J Anderson Karen C Arden John Blenis Michael E Greenberg 1999Cell1999,,6:2
3Variation in the chloride threshold level for steel corrosion in concrete arising from different chloride sources显示文摘RYOU J S ANN K Y 2008Magazine of Con- crete Research2008,60,:1
4Making sense of latent TGF-beta activation显示文摘 MUNGER J S RIFKIN D B 2003J Cell Sci2003,116,2:1
5Progress in Ingorganic Chemistry 显示文摘VINCENT L P ANN J S BRAIN R G 199745:83 -1761997,45,:1
6Phylogenetic relationships in the genus Rosa:new evidence from chloroplast DNA sequences and an appraisal of current knowledge显示文摘ANNE B JUKIAN R S SIMON J 2007Sysematic Botany2007,32,2:1
7Processing of hardmetal coatings on steel substrates 显示文摘Put S Vleugels J Anne G 2003Scripta Materialia2003,48,9:1
8Progress with gene-product mapping of the Mollicutes:Mycoplasma genitalium显示文摘Wasinger V C Cordwell S J Anne C D 1995Electrophoresis1995,16,17:1
9The importance of chloride content at the concrete surface in assessing the time to corrosion of steel in concrete structures显示文摘Ann K Y Ahn J H Ryou J S 2009Construction and Building Materials2009,23,1:1
10The effect of smoking on the transcriptional regulation of lung inflammation in patients with chronic obstructive pulmonary disease 显示文摘Patryk S Ann J Crowther L 2006Am J Respir Crit Care Med2006,,1:1
11The importance of chloride content at the concrete surface in assessing the time to corrosion of steel in concrete structures显示文摘Ann K Y Ahn J H Ryou J S 2009Construction and Building Materials2009,23,1:1
12Contactless impedance measurement by magnetic indution-a possible method for investigation of brain impedance显示文摘 Fornert E Haagem ann S 1993Physiol Meas1993,14,:1
13The role of experiential value in online shopping:The impacts of product presentation on consumer responses towards an apparel, web site显示文摘So Won J eong Ann Marie Fiore Linda S Niehm and Frederick O Lorenz 2009Internet Research2009,19,1:1
14Variation in the chloride threshold lev- el for steel corrosion in concrete arising from different chloride sourees显示文摘RYOU J S ANN K Y 2008Magazine of Concrete Research2008,60,3:1
15An examination of the evidence -based literacy research in deaf education 显示文摘Ann M Cooney S J Young John 2006American Annals of the Deaf2006,,5:1
16LcrV capture enzyme-linked immuno-sorbent assay for detection of Yersinia pestis from human samples显示文摘0 Maria J C Solecki G Anne G S 2005Clin Diagn Lab Immunol2005,12,2:1
17Neurotoxicity of sodium fluoride in rat 显示文摘Mullenix P J Pamele K D Ann S 1995Neurotoxicology and teralogy1995,17,2:1
18Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family显示文摘S?ren S. Larsen Mikala Egeblad Marja J??ttel? Anne E. Lykkesfeldt 1999Breast Cancer Research and Treatment1999,,1:1
19Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss ) digest and metabolize nutrients differently: Effects of water salinity and dietary starch level 显示文摘Ashild K Anne S Jan J O 2004Aquacul- ture2004,229,14:1
20Quantitative assessment of growth factors in reaming aspirate,iliac crest, and platelet prepara- tion显示文摘Schmidmaier G Herm~ann S Green J 2006Bone2006,39,5:1
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