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| 1 | Alcoholic pancreatitis:A tale of spirits and bacteria显示文摘Alcohol is a major cause of chronic pancreatitis.About5%of alcoholics will ever suffer from pancreatitis,suggesting that additional co-factors are required to trigger an overt disease.Experimental work has implicated lipopolysaccharide,from gut-derived bacteria,as a potential co-factor of alcoholic pancreatitis.This review discusses the effects of alcohol on the gut flora,the gut barrier,the liver-and the pancreas and proposes potential interventional strategies.A better understanding of the interaction between the gut,the liver and the pancreas may provide valuable insight into the pathophysiology of alcoholic pancreatitis. | Alain Vonlaufen Laurent Spahr Minoti V Apte Jean-Louis Frossard | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，2： | 3 |
| 2 | Ribavirin:Past,present and future显示文摘Before the advent of direct acting antiviral agents(DAAs) ribavirin, associated to pegylated-interferon played a crucial role in the treatment of chronic hepatitis C, preventing relapses and breakthroughs. In the present era of new potent DAAs, a place is still devoted to the drug. Ribavirin associated with sofosbuvir alone is efficient in the treatment of most cases of G2 infected patients. All options currently available for the last difficult-to-treat cirrhotic G3 patients contain ribavirin. Reducing treatment duration to 12 wk in G1 or G4 cirrhotic compensated patients is feasible thanks to ribavirin. Retreating patients with acquired anti NS5 A resistance-associated variants using ribavirin-based strategies could be useful. The addition of ribavirin with DAAs combinations however, leads to more frequent but mild adverse events especially in cirrhotic patients. Preliminary data with interferon-free second generation DAAs combinations without ribavirin suggest that future of the drug is jeopardized even in difficult-totreat patients: The optimization of ribavirin dosage according to an early monitoring of blood levels has been suggested to be relevant in double therapy with peginterferon or sofosbuvir but not with very potent combinations of more than two DAAs. | Véronique Loustaud-Ratti Marilyne Debette-Gratien Jérémie Jacques Sophie Alain Pierre Marquet DenisSautereau Annick Rousseau Paul Carrier | 2016 | World Journal of Hepatology2016，8，2： | 3 |
| 3 | HCV ‐associated B ‐cell non‐ H odgkin lymphomas and new direct antiviral agents显示文摘 | Paul Carrier Arnaud Jaccard Jérémie Jacques Tessa Tabouret Marilyne Debette‐Gratien Julie Abraham Laura Mesturoux Pierre Marquet Sophie Alain Denis Sautereau Marie Essig Véronique Loustaud‐Ratti | 2015 | Liver Int2015，，10： | 2 |
| 4 | The capsanthin-capsorubin synthase gene: a candidate gene for the y locus controlling the red fruit colour in pepper显示文摘 | Véronique Lefebvre Marcel Kuntz Bilal Camara Alain Palloix | 1998 | Plant Molecular Biology1998，，5： | 2 |
| 5 | Effect of neurotropin on cerebral edema,calcium and other elements in mice subarachnoidally injected with carrageenan显示文摘 | Pierre S Alain K L Stijn V L | 1995 | Euro J Pharmacology1995，274，13： | 1 |
| 6 | Analog sensor design proposal for laser Doppler velocimetry 显示文摘 | Alain L D Guy P Jean C V | 2004 | IEEE Sensors Journal2004，4，2： | 1 |
| 7 | Molecular mecha- nisms of pancreatitis : Current opinion 显示文摘 | Alain V Jeremy S W Minoti V A | 2008 | 2I Gastroen- terol Hepatol2008，23，9： | 1 |
| 8 | Non-contact handling in microassembly: acoustical levitation 显示文摘 | Vincent V Pierre L Alain D | 2005 | Precision Engineering2005，29，4： | 1 |
| 9 | Analog sensor design proposal for laser doppler velocimetry显示文摘 | ALAIN L D GUY P JEAN C V | 2004 | IEEE Sensors Journal2004，4，2： | 1 |
| 10 | Oral fluid testing for driving under the influenceof drugs:history,recent progress and remaining challenges显示文摘 | Alain G V | 2005 | Forensic Sci Int2005，150，23： | 1 |
| 11 | Lesst-Mean- Squares Phase Unwrapping by Use of an Incomplete Set of Residue Branch Cuts 显示文摘 | Igor V Lyuboshenko Henri Matre Alain Maruani | 2002 | Applied Optics2002，41，11： | 1 |
| 12 | From 8-hydroxy-5-sulfoquinoline to new related fluorogenic ligands for complex- ation of aluminium(III) and gallium(III) 显示文摘 | Launay F Alain V Destandau_E | 2001 | New J Chem2001，25，10： | 1 |
| 13 | Analysis of interactions between damage and basic creep of HPC and I-IPFRC heated between 20 and 80 ~C显示文摘 | Wahid L Thierry V Alain S | 2013 | Materials and Structures2013，46，1： | 1 |
| 14 | Penetrating chest trauma:A 20 year ex-perience显示文摘 | Richard B Leon D Alain V | 1987 | J Trauma1987，27，： | 1 |
| 15 | The first encapsulation of hydroxynitrile lyase from Hevca brasiliensis in a sol-gel matrix显示文摘 | Lars V Ulf H Alain P | 2004 | Tetrahedron2004，60，10： | 1 |
| 16 | On the nonlinear deformations of thin unsymmetric 0/90 composite plates under hygrothermal loads 显示文摘 | Marco G Jerome M Frederic J Alain V | 2006 | Composites Part A2006，37，4： | 1 |
| 17 | NOD2/CARD15 gene polymorphisms in Crohn’s disease: a genotype–phenotype analysis显示文摘 | Denis Heresbach Véronique Gicquel-Douabin Brigitte Birebent Pierre-Nicolas D’halluin Nathalie Heresbach-Le Berre Stéphane Dreano Laurent Siproudhis Alain Dabadie Michel Gosselin Jean Mosser Gilbert Semana Jean-Fran?ois Bretagne Jacqueline Yaouanq | 2004 | European Journal of Gastroenterology & Hepatology2004，，1： | 1 |
| 18 | Non-contact handling in microassembly: Acoustical levitation显示文摘 | VINCENT V PIERRE L ALAIN D | 2005 | Precision Engineering2005，29，： | 1 |
| 19 | Antifouling Activities and Inhibition of Mytilis Phenoxidase Marine Biotechnology 显示文摘 | Frederic Z Claire H Alain V | 2002 | Marine Biotechnology2002，4，04： | 1 |
| 20 | On the nonlineardeformations of thin unsymmetric 0/90composite plates underhygrothermal loads显示文摘 | Marco G Jerome M Frédéric J Alain V | 2006 | Composites Part A2006，37，4： | 1 |
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