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| 1 | Molecular basis for identification of species/isolates of gastrointestinal nematode parasites显示文摘Gastrointestinal(GI) parasitism is the most serious constraint throughout the world in small ruminants which causes significant production loss in animals.GI parasites are major contributor to reduce productivity in terms of meat,milk and wool in animals.Control of GI parasite is done primarily by anthelmintic treatment where choice and schedule of treatment is done after identification and quantitation of individual parasite.Identification of GI parasites is done through microscopic method by identifying specific morphological characteristics of egg and larva(L3).Since most of parasite eggs are having similar morphological characteristics, identification up to species level through microscopy is not possible in most of cases.To address this issue,molecular techniques are the viable alternative for identification of species as well as molecular level differences within a species(isolates) of parasites.Different DNA based molecular techniques viz.PCR,AFLP,RAPD,RFLP,PCR-SSCP,real time PCR,DNA microarray etc.have been used for identification and to assess the genetic diversity among parasite population.For identification of species,the characteristic sequence of genomic DNA of different species should differ to allow the delineation of species,but at the same time,no/minor variation within the species should exist.In contrast,for purpose of identifying population variants(strains/isolates), a considerable degree of variation in the sequence should exist within a species.Various target regions,including nuclear ribosomal DNA(rDNA),mitochondrial DNA(mtDNA) or repetitive DNA elements(microsatellite loci),which show considerable variation in the number of repeats within individuals have been employed to achieve the identification of parasites species or strain. | Ahmed M Singh MN Bera AK Bandyopadhyay S Bhattacharya D | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，8： | 6 |
| 2 | HBV vaccine efficacy and detection and genotyping of vaccineé asymptomatic breakthrough HBV infection in Egypt显示文摘AIM:To evaluate the impact of mass vaccination against the hepatitis B virus (HBV) in Egypt,and to search for vaccinee asymptomatic breakthrough HBV infection and its genotype.METHODS:Seven hundred serum samples from vaccinated children and adults (aged 2-47 years) were used for quantitative and qualitative detection of HBsAb by ELISA.Three hundred and sixty serum samples representing undetectable or low or high HBsAb were screened for markers of active HBV infection (HBsAg,HBcAb (IgG) and HBeAb by ELISA,plus HBsAg by AxSYM) and HBV-DNA genotyping by nested multiplex PCR and by DNA sequencing.RESULTS:It was found that 65% of children aged 2-4 years,and 20.5% aged 4-13 years,as well as 45% adults were good responders to HBV vaccination mounting protective level HBsAb.Poor responders were 28%,59.5% and 34%,and non-responders were 7%,20% and 21% respectively,in the three studied groups.Markers of asymptomatic HBV infections were HBsAg detected by ELISA in 2.5% vs 11.39% by AxSYM.Other markers were HBcAb (IgG) in 1.38%,HBeAb in 0.83%,and HBV-DNA in 7.8%.All had HBV genotype E infection.CONCLUSION:It is concluded that HBV vaccine is efficient in controlling HBV infection among children and adults.The vaccine breakthrough infection was by HBV genotype E.A booster dose of vaccine is recommended,probably four years after initial vaccination. | Eman AE Abushady Magda MA Gameel John D Klena Salwa F Ahmed Kouka SE Abdel-wahab Sanya M Fahmy | 2011 | World Journal of Hepatology2011，3，6： | 5 |
| 3 | 抑郁症的非药物治疗:系统性综述与证据图显示文摘背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述,回顾了随机对照试验(RCT),比较抑郁症非药物治疗的有效性和认知行为治疗(CBT)。对多个电子数据库在2016年2月之前发表的所有文献进行了检索,不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT,纳入了约2000名患者,进行了11种治疗,导出17项独立的头对头比较。通过标准化的量表评估,发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而,这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高,导致证据的质量只是低到中等,限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状,在轻度到重度抑郁症患者中,应当合并抗抑郁药物治疗,一同进行。对于非药物治疗的选择,应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。 | Wigdan H Farah Mouaz Alsawas Maria Mainou Fares Alahdab Magdoleen H Farah Ahmed T Ahmed Essa A Mohamed Jehad Almasri Michael R Gionfriddo Ana Castaneda-Guarderas Khaled Mohammed Zhen Wang Noor Asi Craig N Sawchuk Mark D Williams Larry J Prokop M Hassan Murad Annie LeBlanc | 2017 | 英国医学杂志中文版2017，20，11： | 2 |
| 4 | Angiopoietin-1 opposes VEGF-induced increase in endothelial permeability by inhibiting TRPC1-dependent Ca2+ influx显示文摘 | Jho D Mehta D Ahmmed G Gao XP Tiruppathi C Broman M | 2005 | Circ Res2005，96，12： | 1 |
| 5 | Multivariate multiscale entro py a tool for complexity analysis of multichannel data显示文摘 | AHMED M U MANDIC D P | 2011 | Phys Rev E Stat Nonlin Soft Matter Phys2011，84，61： | 1 |
| 6 | Modulation of sterol regulatory element binding proteins (SREBPs) as potential treatments for non- alcoholic fatty liver disease (NAFLD) 显示文摘 | Ahmed M H Byrne C D | 2007 | Dru Discov Today2007，12，17： | 1 |
| 7 | Dermal wound healing processes with curcumin incorporated collagen films 显示文摘 | Gopinath D Ahmed M R Gomathi K | 2004 | Biomaterials2004，25，10： | 1 |
| 8 | Integrated power, water and salt generation: a discussion paper显示文摘 | Ahmed M Arakel A Hoey D | 2001 | Desalination2001，134，1： | 1 |
| 9 | Multivariate multiscale entropy analysis显示文摘 | Ahmed M U Mandic D P | 2012 | IEEE Signal Processing Letters2012，19，2： | 1 |
| 10 | Dermal Wound Healing Processes with Curcumin Incorporated Collagen Films显示文摘 | Gopinath D Rafiuddin Ahmed M Gomathi K | 2004 | Biomaterials2004，25，10： | 1 |
| 11 | The disutility of chronic gout 显示文摘 | KHANNA D AHMED M YONTZ D | 2008 | @al Life Res2008，17，： | 1 |
| 12 | Der- mal wound healing proeesseswith curcumin incorporated collagen films显示文摘 | Gopinath D Rafiuddin Ahmed M Gomathi K | 2004 | Biomaterials2004，25，10： | 1 |
| 13 | Lamivudine prophylaxis against reinfection in liver transplantation for hepatitis B cirrhosis显示文摘 | L Grellier D Mutimer M Ahmed D Brown AK Burroughs K Rolles P McMaster P Beranek F Kennedy H Kibbler P McPhillips E Elias G Dusheiko | 1996 | 1996 (9036)1996，，9036： | 1 |
| 14 | Theory of conductionin polysilicon: drift-diffusion approach in crystallineamorphous-crystalline semiconductor system Part I: small signaltheory显示文摘 | Kim D M Khondker A N Ahmed S S | 1984 | IEEE Transactions on Electron Devices1984，31，4： | 1 |
| 15 | Dynamic measurement of computer generated image segmentations 显示文摘 | Levine Martin D Nazif Ahmed M | 1985 | IEEE Transactions on Pattern Analysis and Machine Intelligence(S0162-8868)1985，7，2： | 1 |
| 16 | Improving Canino Apricot trees productivity by foliar spray with boron,GA3 and active dry yeast显示文摘 | HASSAN H S MOSTAFA E A AHMED D M | 2005 | Arab Universities Journal of Agricultural Sciences2005，13，2： | 1 |
| 17 | Influence of Heat Input and Travel Speed on Mierostructure and Mechanical Properties of Double Tandem Submerged Arc High Strength Low Alloy Steel Weldments 显示文摘 | Viano D M Ahmed N U Schumann G O | 2000 | Science and Technology of Welding and Joining2000，5，1： | 1 |
| 18 | Validation of the indirect TaSP enzyme-linked immunosorbent assay for diagnosis of Theileria annulata infection in cattle 显示文摘 | Salih D E A Ahmed J S Bakheit M A | 2005 | Parasitol Res2005，97，4： | 1 |
| 19 | A rare case of squamous cell carcinoma of the lung harbouring ALK and BRAF activating mutations显示文摘 | Alrifai D Popat S Ahmed M | 2013 | Lung Cancer2013，80，3： | 1 |
| 20 | Brine disposal from reverse osmosis desalination plants in Oman and the United Arab Emirates 显示文摘 | Ahmed M Shayya W H Hoey D | 2001 | Desalination2001，133，2： | 1 |
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