|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 胃癌预防亚太地区共识指南显示文摘背景与目的:胃癌是亚太地区的主要健康负担之一,但对其预防策略尚缺乏共识。本共识会议旨在评价预防胃癌的策略。方法:多学科专家组应用德尔菲(Delphi)法制订共识条文,提呈相关数据,对证据等级、推荐强度以及共识水平予以分级。结果:幽门螺杆菌(H.pylori)感染是非贲门胃腺癌必要但非充分的致病因子。盐的高摄入与胃癌强烈相关。新鲜果蔬对胃癌具有预防作用,但维生素和其他饮食补充并不能预防胃癌。H.pylori感染中的宿主-细菌相互作用导致不同类型的胃炎和胃酸分泌,从而决定疾病结局。胃癌阳性家族史是一个重要的危险因素。低血清胃蛋白酶原反映胃萎缩程度,可作为检出胃癌高危人群的标志物。H.pylori筛查和治疗被推荐作为减少高危人群胃癌危险性的一种策略,该策略在萎缩性胃炎发生前实施最为有效,但并不排除对胃癌高危人群的内镜监测。对胃癌低危人群不推荐行H.pylori筛查。H.pylori感染的一线治疗应遵循国家治疗指南。结论:高危人群中H.pylori筛查和根除策略可能会减少胃癌的发生率,本共识根据现有证据予以推荐。 | Kwong Ming Fock Nick Talley Paul Moayyedi Richard Hunt Takeshi Azuma Kentaro Sugano Shu Dong Xiao Shiu Kum Lam Khean Lee Goh Tsutomu Chiba Naomi Uemura Jae G Kim Nayoung Kim Tiing Leong Ang Varocha Mahachai Hazel Mitchell Abdul Aziz Rani Jyh Ming Liou Ratha-korn Vilaichone Jose Sollanor 钱本余 | 2008 | 胃肠病学2008，13，4： | 37 |
| 2 | mRNA expression of DOK1-6 in human breast cancer显示文摘AIM:To examine the expression of downstream of tyrosine kinase(DOK)1-6 genes in normal and breast cancer tissue and correlated this with several clinicopathological and prognostic factors.METHODS:DOK1-6 m RNA extraction and reverse transcription were performed on fresh frozen breast cancer tissue samples(n = 112) and normal background breast tissue(n = 31). Tissues were collected between 1991 and 1996 at two centres and all patients underwent mastectomy and ipsilateral axillary node dissection. All tissues were randomly numbered and the details were only made known after all analyses were completed. Transcript levels of expression were determined using real-time polymerase chain reaction and analyzed against TNM stage, tumour grade and clinical outcome over a 10-year follow-up period.RESULTS:DOK-2 and DOK-6 expression decreased with increasing TNM stage. DOK-6 expression decreased with increasing Nottingham Prognostic Index(NPI) [NPI-1 vs NPI-3(mean copy number 15.4 vs 0.22, 95%CI:2.7-27.6, P = 0.018) and NPI-2 vs NPI-3(mean copy number 7.6 vs 0.22, 95%CI:0.1-14.6, P = 0.048)]. After a median follow up period of 10 years, higherlevels of DOK-2 expression were found among patients who remained disease-free compared to those who developed local or distant recurrence(mean copy number 3.94 vs 0.0000096, 95%CI:1.0-6.85, P = 0.0091), and distant recurrence(mean copy number 3.94 vs 0.0025, 95%CI:1.0-6.84, P = 0.0092). Patients who remained disease-free had higher levels of DOK-6 expression compared to those who died from breast cancer.CONCLUSION:Decreasing expression levels of DOK-2 and DOK-6 with increased breast tumour progression supports the notion that DOK-2 and DOK-6 behave as tumour suppressors in human breast cancer. | Tamara Ghanem James Bracken Abdul Kasem Wen G Jiang Kefah Mokbel | 2014 | World Journal of Clinical Oncology2014，5，2： | 3 |
| 3 | Role of soil microbes in the rhizospheres of plants growing on trace metal contaminated soils in phytoremediation显示文摘 | Abdul G Khan | 2005 | Journal of Trace Elements in Medicine and Biology2005，15，： | 1 |
| 4 | Journal of Photochemistry and Photo-biology C:Photochemistry Reviews显示文摘 | Umar I G Abdul H A | 2008 | 9(1):12008，9，1： | 1 |
| 5 | Thermal sterilization of canned food in a 3-D pouch using computational fluid dynamics显示文摘 | ABDUL GHANI A G FARID M M CHEN X D | 2001 | Journal of Food Engineering2001，48，2： | 1 |
| 6 | Using the computational fluid dynamics to analyze the thermal sterilization of-solid-liquid food mixture in cans显示文摘 | ABDUL GHANI A G FARID M M | 2006 | Innovative Food Science & Emerging Technologies2006，7，12： | 1 |
| 7 | Ranganathan, modified SVPWM algorithm for three level VSI with synchronized and symmetrical waveforms显示文摘 | Abdul Rahiman Beig G Narayanan V T | 2007 | IEEE Transactions on Industrial Electronics2007，54，1： | 1 |
| 8 | Numerical simulation of transient temperature and velocity profiles in a horizontal can during sterilization using computational fluid dynamics显示文摘 | ABDUL GHANI A G FARID M M CHEN X D | 2002 | Journal of Food Engineering2002，51，1： | 1 |
| 9 | The effect of biodiesel oxi- dation on engine performance and emissions显示文摘 | ABDUL M JON H VAN G | 2001 | Biomass Bioenergy2001，，20： | 1 |
| 10 | Accumulation and implica- tions of cadmium, cobalt and manganese in soils and vegetables irrigated with city effluent显示文摘 | Ghulam M Abdul G Manzoor Q | 2008 | J Sci Food Agr2008，88，： | 1 |
| 11 | A new computational technique time in canned food显示文摘 | FARID M M ABDUL GHANI A for the estimation of sterilization G | 2004 | Chemical Engineering and Processing2004，43，4： | 1 |
| 12 | Protective effect of quercetin in primary neurons against Ap(1-42):rele-vance to Alzheimer’s disease显示文摘 | Ansari MA Abdul HM Joshi G | 2009 | J Nutr Biochem2009，20，4： | 1 |
| 13 | Role of Soil Microbes in the Rhizospheres of Plants Growing on Trace Metal Contaminated Soils in Phytoremediation 显示文摘 | ABDUL G K | 2005 | Journal of Trace Elements in Medi- cine and Biology2005，18，4： | 1 |
| 14 | Computing call-blocking probabilities in LEO satellite constellations 显示文摘 | ABDUL H Z HARRY G E GEORGE N R | 2003 | IEEE Transactions on Vehicular Technology2003，53，3： | 1 |
| 15 | A computational and experimental study of heating and cooling cycles during thermal sterilization of liquid foods in pouches using CFD显示文摘 | ABDUL GHANI A G FARID M M CHEN X D | 2003 | Journal of Process Mechanical Engineering2003，217，1： | 1 |
| 16 | Distributed control of modular and reconfigurable robot with torque sensing 显示文摘 | LIU G J ABDUL S GOLDENBERG A A | 2008 | Robotica2008，26，： | 1 |
| 17 | Evaluation of transdermal targeted niosomal drug delivery of terbinafine hydrochloride显示文摘 | Abdul A Sathali H Rajalakshmi G | | 0，，03： | 1 |
| 18 | Biodegradation of hydrocarbons in soil by microbial consortium显示文摘 | FARINAZLEEN M G Raja Noor Zaliha Abdul Rahman | 2004 | International Biodeterioration & Biodegradation2004，54，： | 1 |
| 19 | Collagen degradation in the abdominal aneurysm:a conspiracy of matrix metalloproteinase and cysteine collagenases显示文摘 | ABDUL HUSSIEN H SOEKHOE R G WEBER E | 2007 | Am J Pathol2007，170，3： | 1 |
| 20 | An integrated NDEand FP3M characterization of composite rotors 显示文摘 | Abdul Aziz A Baaklini G Y Trudell | 2001 | Pro-ceedings of SPIE2001，43，36： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员