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| 1 | 土壤中污染物迁移模型在油田环境影响评价中的应用显示文摘在石油的生产、运输、贮存以及炼制等过程中都存在泄油、漏油风险,各生产过程中的废弃物,如油类、重金属等各种化学物质也会危害水土环境,进而危及当地地下水源。文章分析了油田企业污染物对土壤及地下水的主要污染途径,提出了将污染物在土壤中的迁移模型用于预测污染物浓度的方法。建立了污染物由土壤迁至室内空气、地下水、农作物及由地下水转移到地表水的迁移数学模型,该模型可以运用于油田环境影响评价。 | 张鹏新 Per Aagaard | 2005 | 油气田环境保护2005，15，4： | 7 |
| 2 | Implementation of an in-house flow cytometric analysis of DNA fragmentation in spermatozoa显示文摘An increased amount of DNA fragme ntation in the spermatozoa(SDF)is linked to male in fertility.The Sperm Chromati n Structure Assay(SCSA)is widely used for analysis of SDF.However,the current software(SCSASoftR)linked to this assay is licensed and often located within larger diagnostic centers.In this study,we present a protocol for using other types of software than SCSASoftR to determine the SDF index(DFI)with clinical relevance.This protocol is engineered after collect!ng and analyzing 254 samples from fertility patients and sperm donors over a 15-month period.DFI is analyzed using a strict protocol where the spermatozoa are treated with a strong acid(pH 1.2)followed by acridine orange.DFI is determined by a standard flow cytometric software,FACSDiva 6.1.3.Analysis of the outcome of the fertility treatment is included for 137 patients receiving either intrauterine inseminations(IUI)or timed coitus(TC).The results show that the chance of pregnancy decli nes as DFI in creases.We also found that the male DFI affects the chanee of pregnancy independent of the female age.We have shown that a standard flow cytometric software can be used when determi ning a clinical releva nt DFI.These findings are a sign ificant step toward impleme nting the an alysis as a part of the routi ne,in・house diag no sing of the male fertility patient and subseque ntly optimizing the treatme nt course of the couple with reduced human and financial costs. | Anne Sofie Rex Chunsen Wu Jorn Aagaard Jens Fedder | 2020 | Asian Journal of Andrology2020，22，3： | 5 |
| 3 | 中国的酸化问题——一项基于重庆—广州森林监测点研究结果的评估显示文摘中国经济的快速增长一直伴随着污染的加剧。本文在现场观测和文献研究的基础上讨论了酸性降水及其先兆的范围和影响。目前酸性降水的主要原因是二氧化硫的排放,但氮氧化物的排放也在增加。中国污染最严重地区的硫化合物沉降比东欧和中欧经受严重污染的地区要高。中国南部很多地区的土壤和土壤水看来已经被酸化。这些地区的污染已经影响了森林和其他植物的生命力,特别是在位于和靠近城市地区的地方。地表水的酸化似乎在近期不会成为主要的区域性问题,但一些地区的河流,目前虽仅接受少量的酸沉降,却对酸化显得较敏感。 | Hans M. Seip Per Aagaard Valter Angell Odd Eilertsen ThorjφrnLarssen Espen Lydersen Jan Mulder Ivar P. Muniz Arne Semb 汤大钢 Rolf D. Vogt 肖劲松 赵大为 孔国辉 岳欣 | 1999 | AMBIO-人类环境杂志1999，28，6： | 5 |
| 4 | Spinal and supraspinal control of motor function during maximal eccentric muscle contraction:Effects of resistance training显示文摘Neuromuscular activity is suppressed during maximal eccentric(ECC)muscle contraction in untrained subjects owing to attenuated levels of central activation and reduced spinal motor neuron(MN)excitability indicated by reduced electromyography signal amplitude,diminished evoked H-reflex responses,increased autogenic MN inhibition,and decreased excitability in descending corticospinal motor pathways.Maximum ECC muscle force recorded during maximal voluntary contraction can be increased by superimposed electrical muscle stimulation only in untrained individuals and not in trained strength athletes,indicating that the suppression in MN activation is modifiable by resistance training.In support of this notion,maximum ECC muscle strength can be increased by use of heavy-load resistance training owing to a removed or diminished suppression in neuromuscular activity.Prolonged(weeks to months)of heavy-load resistance training results in increased H-reflex and V-wave responses during maximal ECC muscle actions along with marked gains in maximal ECC muscle strength,indicating increased excitability of spinal MNs,decreased presynaptic and/or postsynaptic MN inhibition,and elevated descending motor drive.Notably,the use of supramaximal ECC resistance training can lead to selectively elevated V-wave responses during maximal ECC contraction,demonstrating that adaptive changes in spinal circuitry function and/or gains in descending motor drive can be achieved during maximal ECC contraction in response to heavy-load resistance training. | Per Aagaard | 2018 | Journal of Sport and Health Science2018，7，3： | 3 |
| 5 | How should liver hypertrophy be stimulated?A comparison of upfront associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)and portal vein embolization(PVE)with rescue possibility显示文摘Background:The role of associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)in comparison to portal vein embolization(PVE)is debated.The aim of this study was to compare successful resection rates(RR)with upfront ALPPS vs.PVE with rescue ALPPS on demand and to compare the hypertrophy of the liver between ALPPS and PVE plus subsequent rescue ALPPS.Methods:A retrospective analysis of all patients treated with PVE for colorectal liver metastasis(CRLM)or ALPPS(any diagnosis,rescue ALPPS included)at five Scandinavian university hospitals during the years 2013-2016 was conducted.A Chi-square test and a Mann-Whitney U test were used to assess the difference between the groups.A successful RR was defined as liver resection without a 90-day mortality.Results:A total of 189 patients were included.Successful RR was in 84.5%of the patients with ALPPS upfront and in 73.3%of the patients with PVE and rescue ALPPS on demand(P=0.080).The hypertrophy of the future liver remnants(FLRs)with ALPPS upfront was 71%(48-97%)compared to 96%(82-113%)after PVE and rescue ALPPS(P=0.010).Conclusions:Upfront ALPPS offers a somewhat higher successful RR than PVE with rescue ALPPS on demand.The sequential combination of PVE and ALPPS leads to a higher overall degree of hypertrophy than upfront ALPPS. | Ernesto Sparrelid Kristina Hasselgren Bård Ingvald Røsok Peter Nørgaard Larsen Nicolai Aagaard Schultz Ulrik Carling Eva Fallentin Stefan Gilg Per Sandström Gert Lindell Bergthor Björnsson | 2021 | Hepatobiliary Surgery and Nutrition2021，10，1： | 2 |
| 6 | A comparison of lower limb stiffness and mechanical muscle function in ACL-reconstructed,elite,and adolescent alpine ski racers/ski cross athletes显示文摘Purpose: The aim of this study was to compare mechanical muscle function in the eccentric/concentric phases of vertical bilateral jumping in anterior cruciate ligament-reconstructed(ACLR), elite(ELITE), and adolescent(ADOL) alpine ski racers and ski cross athletes.Methods: Alpine ski racers/ski crossers(ACLR: n = 12, age = 26.7 § 3.8 years; ELITE: n = 12, age = 23.9 § 3.0 years; ADOL: n = 12, age = 17.8§ 0.7 years; females: n = 6 per group, males: n = 6 per group) performed 5 maximal countermovement jumps(CMJs) and 5 squat jumps. The ground reaction forces for each limb were analyzed using dual force plate recording to obtain body center of mass(BCM) velocity, displacement,and power. The eccentric deceleration(ECC) and concentric phases were determined from BCM velocity. CMJ net concentric and ECC impulses were calculated(body mass normalized) along with the peak and mean BCM power and maximal vertical jump height. CMJ lower limb stiffness(LLS) was determined by the slope of the ground reaction forces vs. the BCM displacement curve over the ECC phase. Concentric and ECC asymmetry indices were calculated for each leg, and the left vs. right LLS was compared. Outcome measures(reported as mean § SD) calculated as a 5-jump mean were normalized to body mass and compared using an analysis of variance.Results: No between-group differences were found for peak and mean power or jump heights. There were no group differences for LLS or net concentric phase impulse, but the net ECC impulse was lower in the ADOL group compared with ELITE skiers(ADOL: 1.33 § 0.32 Ns/kg;ELITE: 1.59 § 0.16 Ns/kg; p < 0.05). Although no group differences were found for ECC asymmetry indices, a group ￡ limb interaction was found for LLS(p < 0.01), which was systematically higher in the right vs. the left limb of ADOL skiers(right: 54.1 § 17.9 N/m/kg; left: 48.7 §15.7 N/m/kg; p < 0.01).Conclusion: ADOL skiers demonstrated decreased ECC impulse and systematic right limb dominance in LLS compared with ACLR and ELITE skiers. The implication of these findings for injury and performance are unknown, but further investigation into these potential relationships is warranted. | matthew j.jordan per aagaard walter herzog | 2018 | Journal of Sport and Health Science2018，7，4： | 2 |
| 7 | Performance-based Research Funding in Denmark: The Adoption and Translation of the Norwegian Model显示文摘Purpose: The main goal of this study is to outline and analyze the Danish adoption and translation of the Norwegian Publication Indicator. Design/methodology/approach: The study takes the form of a policy analysis mainly drawing on document analysis of policy papers, previously published studies and grey literature. Findings: The study highlights a number of crucial factors that relate both to the Danish process and to the final Danish result underscoring that the Danish BFI model is indeed a quite different system than its Norwegian counterpart. One consequence of these process-and design differences is the fact that the broader legitimacy of the Danish BFI today appears to be quite poor. Reasons for this include: unclear and shifting objectives throughout the process; limited willingness to take ownership of the model among stakeholders; lack of communication throughout the implementation process and an apparent underestimation of the challenges associated with the use of bibliometric indicators. Research limitation: The conclusions of the study are based on the authors' interpretation of a long drawn and complex process with many different stakeholders involved. The format of this article does not allow for a detailed documentation of all elements, but further details can be provided upon request. Practical implications: The analysis may feed into current policy discussions on the future of the Danish BFI. Originality/value: Some elements of the present analysis have previously been published in Danish outlets, but this article represents the first publication on this issue targeting a broader international audience. | Kaare Aagaard | 2018 | Journal of Data and Information Science2018，3，4： | 2 |
| 8 | Passive energy return after repeated stretches of the hamstring muscle-tendon unit 显示文摘 | MAGNUSSON S P AAGAARD P NIELSON J J | 2000 | Medi- cine and Science in Sports and Exercise2000，32，6： | 1 |
| 9 | A multistage tuberculosis vaccine that confers efficient protection before and after exposure, 显示文摘 | Aagaard C Hoang T Dietrich J | 2011 | Nat Med2011，17，2： | 1 |
| 10 | Origin and migration of brines from Paleozoic strata in Central Tarim, China: constraints from 87Sr/86Sr, δD, δ18O and water chemistry 显示文摘 | Cai C Franks S G Aagaard P | 2001 | Applied Geochemistry2001，16，9： | 1 |
| 11 | Expanding the use of totalmitral valve reservation in combination with implantation of the Car-bomedics heart valve prosthesis显示文摘 | Aagaard J Andersen UL Lerbjerg G | 1999 | J Cardiovasc Surg(Torino)1999，42，2： | 1 |
| 12 | RNAi therapeutics:principles,prospectsand challenges显示文摘 | Aagaard L Rossi JJ | 2007 | Adv Drug Deliv Rev2007，59，： | 1 |
| 13 | Differential displacement of the human soleus and nedial gastrocnemius aponeuroses during isometric plantar flexor contractions in vivo显示文摘 | Moller JB Hansen P Aagaard P | | 0，，： | 1 |
| 14 | Effects of a shelf polynya on flow and water properties in the northern Bering sea 显示文摘 | Schumacher J D Aagaard K Pease C H | 1983 | Journal of Geophysical Research1983，88，5： | 1 |
| 15 | Recanalised umbilical vein in portal hypertension显示文摘 | Aagaard J Jensen LI Christensen U | 1982 | AJR1982，139，： | 1 |
| 16 | Function of the normal meniscus and consequences of meniscal resection显示文摘 | Aagaard H Verdonk R | | 0，，03： | 1 |
| 17 | EHects of strength training on endur-ance capacity in top-level endurance athletes显示文摘 | Aagaard P Andersen J L | 2010 | Scand J Med Sci Sports2010，20，2： | 1 |
| 18 | Expanding the use of total mitral valve preservation in combination with implant at ion of the carbomedics heart valve prosthesis显示文摘 | Aagaard J Andersen UL Lerbjerg G | 1999 | J Cardiovase Surg (Tori- no)1999，40，2： | 1 |
| 19 | Neural adaptation to resistance training: changes in evoked V-wave and H-reflex responses 显示文摘 | Aagaard P Simonsen E B Andersen J L | 2002 | J Appl Physiol2002，92，6： | 1 |
| 20 | Oncogenic alterations of p16INK4/CDKN2 and cyclin D1 cooperate to deregulate G1 control 显示文摘 | Lukas J Aagaard L Strauss M | 1996 | Cancer Res1996，55，21： | 1 |
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