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| 1 | Validation of the Rockall scoring system for outcomes from non-variceal upper gastrointestinal bleeding in a Canadian setting显示文摘AIM: To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS: We used data extracted from the Registry of Upper Gastrointestinal Bleeding and Endoscopy including information of 1869 patients with non-variceal upper gastrointestinal bleeding treated in Canadian hospitals. Risk scores were calculated and used to classify patients based on outcomes. For each outcome, we used χ2 goodness-of-fit tests to assess the degree of calibration, and built receiver operating characteristic curves and calculated the area under the curve (AUC) to evaluate the discriminative ability of the scoring system. RESULTS: For rebleeding, the χ2 goodness-of-fit test indicated an acceptable fit for the model [χ2 (8) = 12.83, P = 0.12]. For surgical procedures [χ2 (8) = 5.3, P = 0.73] and death [χ2 (8) = 3.78, P = 0.88], the tests showed solid correspondence between observed proportions and predicted probabilities. The AUC was 0.59 (95% CI: 0.55-0.62) for the outcome of rebleeding and 0.60 (95% CI: 0.54-0.67) for surgical procedures, representing apoor discriminative ability of the scoring system. For the outcome of death, the AUC was 0.73 (95% CI: 0.69-0.78), indicating an acceptable discriminative ability. CONCLUSION: The Rockall scoring system provides an acceptable tool to predict death, but performs poorly for endpoints of rebleeding and surgical procedures. | Robert A Enns Yves M Gagnon Alan N Barkun David Armstrong Jamie C Gregor Richard N Fedorak RUGBE Investigators Group | 2006 | World Journal of Gastroenterology2006，12，48： | 14 |
| 2 | Genomic and antigenic variations of porcine reproductive and respiratory syndrome virus major envelope GP5 glycoprotein显示文摘 | Pizadeh B Gagnon C A Dea S | 1998 | Can J Vet Res1998，62，3： | 1 |
| 3 | EMG power spectrum as a measure of muscular fatigue at different levels of contraction显示文摘 | Nagata S Arsenault A B Gagnon D | 1990 | Med Biol Eng Comput1990，28，4： | 1 |
| 4 | Antigenic variability among North American and European strains of porcine reproductive and respiratory syndrome virus as defined by monoclonal antibodies to the matrix protein 显示文摘 | Dea S Gagnon C A Mardassi H | 1996 | J Clin Microbiol1996，34，6： | 1 |
| 5 | Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome(PRRS)virus:comparison of the North American and Europe isolates显示文摘 | Dea S Gagnon C A Mardassi H | 2000 | Arch Virol2000，145，4： | 1 |
| 6 | Macrophage - conditioned medium inhibits the differentiation of 3T3 - L1 and human abdominal preadipocytes 显示文摘 | Constant VA Gagnon A Landry A | 2006 | Diabetologia2006，49，6： | 1 |
| 7 | A subset of porcine reproduc- tive and respiratory syndrome vires GP3 glycoprotein is released into the culture medium of cells as a non-virion-associ- ated and membrane-free (soluble) form 显示文摘 | MARDASSI H GONIN P GAGNON C A | 1998 | J Virol1998，72，8： | 1 |
| 8 | Endoscopic laser coagulation in the management of severe twin-to-twin transfusion syndrome 显示文摘 | ViUe Y Hecher K Gagnon A | 1998 | Br J Obstet Gynaecol1998，105，4： | 1 |
| 9 | Antigenic variability among North American and European strains of porcine reproductive and respiratory syndrome virus as defined by monoclonal antibodies to the matrix protein 显示文摘 | Dea S Gagnon C A Mardassi H | 1996 | Journal of clinical microbiology1996，34，： | 1 |
| 10 | Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus: comparison of the North American and European isolates 显示文摘 | Dea S Gagnon C A Mardassi H | 2000 | Arch Virol2000，145，： | 1 |
| 11 | Removal of easily biodegradable organic compounds by drinking water biofilms:analysis of kinetics and transfer显示文摘 | Gagnon G A Huck P M | 2001 | Water Research2001，35，10： | 1 |
| 12 | The emergence of porcine circovirus 2b genotype (PCV-2b) in swine in Canada显示文摘 | Gagnon C A Tremblay D Tijssen P | | 0，，08： | 1 |
| 13 | Formation of ice covers and ice jams in rivers 显示文摘 | Pariset E H ausser R Gagnon A | 1966 | Journal of the Hydraulics Di- vision1966，92，6： | 1 |
| 14 | Development and use of a multiplex real-time quantitative polymerase chain reaction assay for detection and differentiation of porcine circovirus-2 genotypes 2a and 2b in an epidemiological survey显示文摘 | Gagnon C A Del Castillo J R Music N | 2008 | J Vet Diagn Invest2008，20，5： | 1 |
| 15 | TSH-stimulating hormone stimulates lipolysis in adipocytes in culture and raises serum free fatty acid levels in vivo显示文摘 | Gagnon A Antunes TT Ly T | 2010 | Metabolism2010，59，4： | 1 |
| 16 | Adsorption of arsenic from a Nova Scotia groundwater onto water treatment residual solids显示文摘 | Gibbons M K Gagnon G A | 2010 | Water Res2010，44，19： | 1 |
| 17 | Monoclonal antibodies to the GP5 of porcine reproductive and respiratory syndrome virus are more effective in virus neu tralization than monoclonal antibodies to the GP4显示文摘 | Gonin P Pirzadeh B Gagnon C A | 2001 | J Vet Diagn Invest2001，，11： | 1 |
| 18 | Current knowledge on the structural proteins of porcine reproductive and respiratory syndrome (PRRS) virus: comparison of the North American and European isolates 显示文摘 | DEA S GAGNON C A MARDASSI H | 2000 | Arch Virol2000，145，： | 1 |
| 19 | An efficient biofilm removal method for bacterial cells exposed to drinking water显示文摘 | Gagnon G A Slawson R M | 1999 | J Microbiol Methods1999，34，： | 1 |
| 20 | Current knowledge on the structural proteins of porcine reproductive and respira- tory syndrome (PRRS) virus:comparison of the North Ameri can and European isolates 显示文摘 | Dea S Gagnon C A Mardassi H | 2000 | Arch Virol2000，145，4： | 1 |
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