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| 1 | Inflammation, oxidative stress and renin angiotensin system in atherosclerosis显示文摘Atherosclerosis is a chronic inflammatory disease associated with cardiovascular dysfunction including myocardial infarction, unstable angina, sudden cardiac death, stroke and peripheral thromboses. It has been predicted that atherosclerosis will be the primary cause of death in the world by 2020. Atherogenesis is initiated by endothelial injury due to oxidative stress associated with cardiovascular risk factors including diabetes mellitus, hypertension, cigarette smoking, dyslipidemia, obesity, and metabolic syndrome. The impairment of the endothelium associated with cardiovascular risk factors creates an imbalance between vasodilating and vasoconstricting factors, in particular, an increase in angiotensin Ⅱ(Ang Ⅱ) and a decrease in nitric oxide. The renin-angiotensin system(RAS), and its primary mediator Ang Ⅱ, also have a direct influence on the progression of the atherosclerotic process via effects on endothelial function, inflammation, fibrinolytic balance, and plaque stability. Anti-inflammatory agents [statins, secretory phospholipase A2 inhibitor, lipoprotein-associated phospholipase A2 inhibitor, 5-lipoxygenase activating protein, chemokine motif ligand-2, C-C chemokine motif receptor 2 pathway inhibitors, methotrexate, IL-1 pathway inhibitor and RAS inhibitors(angiotensin-converting enzyme inhibitors)], Ang Ⅱ receptor blockers and ranin inhibitors may slow inflammatory processes and disease progression. Several studies in human using anti-inflammatory agents and RAS inhibitors revealed vascular benefits and reduced progression of coronary atherosclerosis in patients with stable angina pectoris; decreased vascular inflammatory markers, improved common carotid intima-media thickness and plaque volume in patients with diagnosed atherosclerosis. Recent preclinical studies have demonstrated therapeutic efficacy of vitamin D analogs paricalcitol in Apo E-deficient atherosclerotic mice. | Kazim Husain Wilfredo Hernandez Rais A Ansari Leon Ferder | 2015 | World Journal of Biological Chemistry2015，6，3： | 84 |
| 2 | 魔芋葡甘聚糖功能材料研究与应用进展显示文摘为了更好地开发利用魔芋葡甘聚糖(KGM),本文阐明了KGM独特的结构、优良的理化性质,分析了其结构与性能的关系, 综述了在食品、化工、医药、石油钻探等应用领域中形成的以KGM为基本组成的功能材料研究进展。并对近几年国内外KGM在该领域的研究动向及其应用前景进行了探讨。 | 庞杰 林琼 张甫生 田世平 孙远明 | 2003 | Chinese Journal of Structural Chemistry2003，22，6： | 120 |
| 3 | Quantum Chemical Study on Geometry and Property of Cluster Ni_4P显示文摘A series of clusters Ni4P are designed to simulate the amorphous alloy Ni80P20. After the cluster models are computed by DFT, several stable structures are gained. Their geometric, electronic and catalytic properties have been analyzed and discussed. It is proved that cluster Ni4P can reflect the amorphous alloy Ni80P20 very well from the geometry parameters. We find the deformed triangle dipyramid with quadruplet state (configuration 1(4)) is the most stable structure for cluster Ni4P, which is the most possible local structure in amorphous alloy Ni80P20. And the transition energy between two isomers with the same multiple state is higher than the one with the different. Bond Ni–P plays a very important role in offering the system stability for cluster Ni4P. P is the electron donor, and Ni is the accepter in cluster Ni4P, which is in accordance with the experiment results. The 3d orbital populations and Fermi levels of clusters Ni4 have been decreased with the addition of atom P. Based on the research of Fermi levels of clusters Ni4P to approach the Fermi level of H2 and their density of state (DOS), the highest catalytic active property in cluster Ni4P is owned to configuration 1(4). | 方志刚 胡红智 郭景雪 | 2006 | Chinese Journal of Structural Chemistry2006，25，1： | 70 |
| 4 | Role of microRNAs in translation regulation and cancer显示文摘MicroRNAs(miRNAs) are pervasively expressed and regulate most biological functions. They function by modulating transcriptional and translational programs and therefore they orchestrate both physiological and pathological processes, such as development, cell differentiation, proliferation, apoptosis and tumor growth. miRNAs work as small guide molecules in RNA silencing, by negatively regulating the expression of several genes both at mRNA and protein level, by degrading their mRNA target and/or by silencing translation. One of the most recent advances in the field is the comprehension of their role in oncogenesis. The number of miRNA genes is increasing and an alteration in the level of miRNAs is involved in the initiation, progression and metastases formation of several tumors. Some tumor types show a distinct miRNA signature that distinguishes them from normal tissues and from other cancer types. Genetic and biochemical evidence supports the essential role of miRNAs in tumor development. Although the abnormal expression of miRNAs in cancer cells is a widely accepted phenomenon, the cause of this dysregulation is still unknown. Here, we discuss the biogenesis of miRNAs, focusing on the mechanisms by which they regulate protein synthesis. In addition we debate on their role in cancer, highlighting their potential to become therapeutic targets. | Stefania Oliveto Marilena Mancino Nicola Manfrini Stefano Biffo | 2017 | World Journal of Biological Chemistry2017，8，1： | 60 |
| 5 | Metal foams: A survey显示文摘The current state-of-the-art in the development of cellular metal foams is reviewed, with focus on their fabrication, mechanical/thermal/acoustic properties, and potential applications as lightweight panels, energy absorbers, heat exchangers, and acoustic liners. Foam property charts with scaling relations are presented, allowing scoping and selection through the use of material indices. | Michael F.Ashby 卢天健 | 2003 | Science China Chemistry2003，46，6： | 45 |
| 6 | Studies on the Physicochemical Properties, Structure and Antitumor Activity of Polysaccharide YhPS-1 from the Root of Cordalis yanhusuo Wang显示文摘多糖说出 YhPS-1 从 Cordalis yanhusuo 王的根被孤立并且借助于胶化浸透净化了层析和 ionexchange 层析。包括 monosaccharide 作文,糖类内容,分子的重量和元素的作文,它的物理化学的性质是坚定的。YhPS-1 的结构被化学方法与 1H 和 13C NMR 光谱学方法一起阐明,例如包括二维的 HMQC 和 HMBC 实验。这些结果证明 YhPS-1 拥有由终端 -Glcp-(1,-Glcp-(16),-Glcp-(14) 和 -Glcp-(14,6) 组成的一根脊梁。bioactive 试金证明它能禁止肉瘤 180 的生长和肺的癌在老鼠植入的路易斯。 | 陶移文 田庚元 | 2006 | Chinese Journal of Chemistry2006，24，2： | 48 |
| 7 | 铝厂污泥在不同煅烧温度的晶相结构研究显示文摘铝厂污泥主要成分是-AlOOH,其中部分是晶体,部分是无定形体。将此污泥分别于450,600,800,1000,1050,1200和1300 ℃进行了煅烧,探讨污泥在不同温度下的晶相变化,为污泥的综合利用提供可靠的数据。采用XRD法和SEM法表征了污泥在不同温度下的晶相结构和显微结构。实验结果表明:随着煅烧温度的提高,污泥发生如下变化过程: 这与常规转化规律不同。在450,600,800,1000和1100 ℃的试样中均形成了-Al2O3和无定形体结构的微晶,随着温度的升高,-Al2O3含量增加而无定形体结构的微晶含量降低。当煅烧温度上升至1200和1300 ℃时, - Al2O3和无定形体结构的微晶全部转变为 - Al2O3。 -Al2O3是介稳态,高活性,-Al2O3是稳定态,低能态。 | 于岩 阮玉忠 黄清明 周敏 杜育红 吴任平 | 2003 | Chinese Journal of Structural Chemistry2003，22，5： | 44 |
| 8 | Mechanism of chain propagation for the synthesis of polyoxymethylene dimethyl ethers显示文摘Polyoxymethylene dimethyl ethers(PODE)were synthesized from the reaction of paraformaldehyde with dimethoxymethane(DMM)over different acid catalysts at different conditions.Products were found to follow the Schulz-Flory distribution law.The chain propagation proceeds through the insertion of an individual segment of CH2O one by one,while the simultaneous insertion of a few CH2O segments or their assembly is unlikely.Due to the restriction of this law,it is difficult to increase the selectivity to the desired products(e.g.,PODE3 4). | Yupei Zhao Zheng Xu Hui Chen Yuchuan Fu Jianyi Shen | 2013 | Journal of Energy Chemistry2013，22，6： | 36 |
| 9 | MXene-based materials for electrochemical energy storage显示文摘Rechargeable batteries and supercapacitors are widely investigated as the most important electrochemical energy storage devices nowadays due to the booming energy demand for electric vehicles and hand-held electronics. The large surface-area-to-volume ratio and internal surface areas endow two-dimensional(2D) materials with high mobility and high energy density; therefore, 2D materials are very promising candidates for Li ion batteries and supercapacitors with comprehensive investigations. In 2011, a new kind of 2D transition metal carbides, nitrides and carbonitrides, MXene, were successfully obtained from MAX phases. Since then about 20 different kinds of MXene have been prepared. Other precursors besides MAX phases and even other methods such as chemical vapor deposition(CVD) were also applied to prepare MXene, opening new doors for the preparation of new MXene. Their 2D nature and good electronic properties ensure the inherent advantages as electrode materials for electrochemical energy storage. In this review, we summarize the recent progress in the development of MXene with emphasis on the applications to electrochemical energy storage. Also, future perspective and challenges of MXene-based materials are briefly discussed regrading electrochemical energy storage. | Xu Zhang Zihe Zhang Zhen Zhou | 2018 | Journal of Energy Chemistry2018，27，1： | 40 |
| 10 | Achieving over 16% efficiency for single-junction organic solar cells显示文摘To achieve high photovoltaic performance of bulk hetero-junction organic solar cells(OSCs), a range of critical factors including absorption profiles, energy level alignment, charge carrier mobility and miscibility of donor and acceptor materials should be carefully considered. For electron-donating materials, the deep highest occupied molecular orbital(HOMO) energy level that is beneficial for high open-circuit voltage is much appreciated. However, a new issue in charge transfer emerges when matching such a donor with an acceptor that has a shallower HOMO energy level. More to this point, the chemical strategies used to enhance the absorption coefficient of acceptors may lead to increased molecular crystallinity, and thus result in less controllable phase-separation of photoactive layer. Therefore, to realize balanced photovoltaic parameters, the donor-acceptor combinations should simultaneously address the absorption spectra, energy levels, and film morphologies. Here, we selected two non-fullerene acceptors, namely BTPT-4F and BTPTT-4F, to match with a wide-bandgap polymer donor P2F-EHp consisting of an imidefunctionalized benzotriazole moiety, as these materials presented complementary absorption and well-matched energy levels. By delicately optimizing the blend film morphology, we demonstrated an unprecedented power conversion efficiency of over 16% for the device based on P2F-EHp:BTPTT-4F, suggesting the great promise of materials matching toward high-performance OSCs. | Baobing Fan Difei Zhang Meijing Li Wenkai Zhong Zhaomiyi Zeng Lei Ying Fei Huang Yong Cao | 2019 | Science China Chemistry2019，62，6： | 38 |
| 11 | Nanostructured energy materials for electrochemical energy conversion and storage: A review显示文摘Nanostructured materials have received tremendous interest due to their unique mechanical/electrical properties and overall behavior contributed by the complex synergy of bulk and interfacial properties for efficient and effective energy conversion and storage. The booming development of nanotechnology affords emerging but effective tools in designing advanced energy material. We reviewed the significant progress and dominated nanostructured energy materials in electrochemical energy conversion and storage devices, including lithium ion batteries, lithium–sulfur batteries, lithium–oxygen batteries, lithium metal batteries, and supercapacitors. The use of nanostructured electrocatalyst for effective electrocatalysis in oxygen reduction and oxygen evolution reactions for fuel cells and metal–air batteries was also included. The challenges in the undesirable side reactions between electrolytes and electrode due to high electrode/electrolyte contact area, low volumetric energy density of electrode owing to low tap density,and uniform production of complex energy materials in working devices should be overcome to fully demonstrate the advanced energy nanostructures for electrochemical energy conversion and storage. The energy chemistry at the interfaces of nanostructured electrode/electrolyte is highly expected to guide the rational design and full demonstration of energy materials in a working device. | Xueqiang Zhang Xinbing Cheng Qiang Zhang | 2016 | Journal of Energy Chemistry2016，25，6： | 35 |
| 12 | Ozone source attribution during a severe photochemical smog episode in Beijing,China显示文摘Beijing,the capital of China,frequently suffers from the high levels of ozone in summer.A 3-D regional chemical transport model,the Comprehensive Air Quality Model with extensions(CAMx),has been used to simulate a heavy O3 pollution episode in Beijing during June 26―July 2,2000.Ozone Source Apportionment Technology(OSAT) and Geographic Ozone Assessment Technology(GOAT) were applied to quantify the contributions of the precursor emissions from different regions to O3 concentrations in Beijing,to identify the relative importance of different ways by which regional sources affected the O3 levels in Beijing urban areas,and to investigate the sensitivity of O3 formation to the precursors during the episode.The O3 pollution in Beijing showed a significant spatial distribution with strong regional contribution.The results suggested that the plume originating from Beijing urban areas greatly affected the O3 concentrations at the Dingling site,accounting for 55% of elevated O3 there,while O3 pollution in the Beijing urban areas resulted from both local emissions and those from Tianjin and the south of Hebei Province.Transport of O3 was responsible for about 70% of the regional O3 contribution to Beijing urban areas,while transport of O3 precursors accounted for the remainder.The formation of O3 was limited by volatile organic compounds(VOCs) in the urban areas of Beijing,while being more sensitive to NOx levels in the suburban and more remote areas.Therefore,it is necessary to consider a large number of factors,including impacts of emissions from different regions,the two modes of regional contribution as well as the sensitivity of O3 formation to precursors,in the design of emissions control strategies for O3 reduction in Beijing. | WANG XueSong LI JinLong ZHANG YuanHang XIE ShaoDong TANG XiaoYan | 2009 | Science China Chemistry2009，52，8： | 32 |
| 13 | Regional ozone pollution and key controlling factors of photochemical ozone production in Pearl River Delta during summer time显示文摘An intensive field campaign including measurements from the environmental monitoring network and from two super sites took place in the Pearl River Delta region in summer 2006.Using routinely measured O3 and NOx concentrations,the spatial and temporal variation of O3 and of the total oxidant concentrations was characterized.According to the spatial variability of NO2/NO,the two super sites were found to be representative of polluted urban and downwind suburban conditions.In addition,both sites were located in high O3 regions.In-depth diagnostic of photochemical ozone production processes and their key controlling factors are achieved with an observation-based model(OBM) to gain regional perspectives.Budget analysis and sensitivity model runs show that aldehyde and HONO chemistry had significant impacts on local photochemical ozone production rates.The analysis of calculated Relative Incremental Reactivities shows that photochemical ozone production rates are mainly sensitive to anthropogenic hydrocarbons(HCs) in the polluted urban areas.In the suburban areas,sensitivity to nitrogen oxide(NO) concentrations dominated.Key anthropogenic HCs in both areas are alkenes and aromatics.Significant differences of ozone production efficiencies are identified between the urban and suburban regions,consistent with the OBM diagnosed results. | CHANG ChihChung CHOU C.K.Charles Andreas Wahner | 2010 | Science China Chemistry2010，53，3： | 34 |
| 14 | TIMING OF COLLISION BETWEEN THE NORTH AND SOUTH CHINA BLOCKS——THE Sm-Nd ISOTOPIC AGE EVIDENCE显示文摘Sm-Nd isotopic ages for C-type eclogite (243.9±5.6 Ma) and mafic and ultramafic rocks(230.6±30.7 Ma and 402.6±17.4 Ma) from the Qinling-Dabieshan orogenic belt are reported.These ages suggest that at the early Triassic, the North and South China Blocks have beenunited along the Qinling-Dabieshan collision zone, and before the final collision, a se-ries of ophiolite obductions took place successively away from the continental marginduring the Paleozoic. | 李曙光 S.R.HART 郑双根 刘德良 张国伟 郭安林 | 1989 | Science China Chemistry1989，32，11： | 33 |
| 15 | Preparation of hierarchical mesoporous Zn/HZSM-5 catalyst and its application in MTG reaction显示文摘The hierarchical mesoporous Zn/ZSM-5 zeolite catalyst was prepared by NaOH treatment and Zn impregnation, and its application in the conversion of methanol to gasoline (MTG) was studied. N2 adsorption-desorption results showed that the mesopores with sizes of 2–20 nm in HZ5/0.3AT was formed by 0.3 M NaOH alkali treatment. The zeolite samples after modification were also characterized by XRF, AAS, XRD, SEM and NH3-TPD methods. Zn impregnated catalyst Zn/HZ5/0.3AT exhibited dramatic improvements in catalytic lifetime and liquid hydrocarbons yield. The selectivity of aromatic hydrocarbons was also improved after Zn impregnation. It is suggested that the mesopores of Zn/HZ5/0.3AT enhanced the synergetic effect of Zn species and acid sites and the capability to coke tolerance, which were confirmed by the results of catalytic test and TGA analysis, respectively. | Youming Ni Aiming Sun XiaolingWu Guoliang Hai Jianglin Hu Tao Li Guangxing Li | 2011 | Journal of Natural Gas Chemistry2011，20，3： | 31 |
| 16 | Methanation of carbon dioxide on Ni/ZrO_2-Al_2O_3 catalysts:Effects of ZrO_2 promoter and preparation method of novel ZrO_2-Al_2O_3 carrier显示文摘The novel nickel-based catalysts with a nickel content of 12 wt% were prepared with the zirconia-alumina composite as the supports. The new carriers, ZrO2 improved alumina, were synthesized by three methods, i.e., impregnation-precipitation, co-precipitation, and impregnation method. The catalytic properties of these catalysts were investigated in the methanation of carbon dioxide, and the samples were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscope (XPS), temperature-programmed reduction (TPR) and temperature-programmed desorption (TPD) techniques. The new catalysts showed higher catalytic activity and better stability than Ni/γ-Al2O3. Furthermore, as a support for new nickel catalyst, the ZrO2-Al2O3 composite prepared by the impregnation-precipitation method was more efficient than the other supports in the methanation of carbon dioxide. The highly dispersed zirconium oxide on the surface of γ-Al2O3 inhibited the formation of nickel aluminate-like phase, which was responsible for the better dispersion of Ni species and easier reduction of NiO species, leading to the enhanced catalytic performance of corresponding catalyst. | Mengdie Cai Jie Wen Wei Chu Xueqing Cheng Zejun Li | 2011 | Journal of Natural Gas Chemistry2011，20，3： | 33 |
| 17 | Synthesis and properties of phosphorus-containing bio-based epoxy resin from itaconic acid显示文摘A phosphorus-containing bio-based epoxy resin(EADI)was synthesized from itaconic acid(IA)and 9,10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide(DOPO).As a matrix,its cured epoxy network with methyl hexahydrophthalic anhydride(MHHPA)as the curing agent showed comparable glass-transition temperature and mechanical properties to diglycidyl ether in a bisphenol A(DGEBA)system as well as good flame retardancy with UL94 V-0 grade during a vertical burning test.As a reactive flame retardant,its flame-resistant effect on DGEBA/MHHPA system as well as its influence on the curing behavior and the thermal and mechanical properties of the modified epoxy resin were investigated.Results showed that after the introduction of EADI,not only were the flame retardancy determined by vertical burning test,LOI measurement,and thermogravimetric analysis significantly improved,but also the curing reactivity,glass transition temperature(T g),initial degradation temperature for 5%weight loss(T d(5%)),and flexural modulus of the cured system improved as well.EADI has great potential to be used as a green flame retardant in epoxy resin systems. | MA SongQi LIU XiaoQing JIANG YanHua FAN LiBo FENG JianXiang ZHU Jin | 2014 | Science China Chemistry2014，57，3： | 33 |
| 18 | New insight in expression, transport, and secretion of brain-derived neurotrophic factor: Implications in brainrelated diseases显示文摘Brain-derived neurotrophic factor(BDNF) attracts increasing attention from both research and clinical fields because of its important functions in the central nervous system. An adequate amount of BDNF is critical to develop and maintain normal neuronal circuits in the brain. Given that loss of BDNF function has beenreported in the brains of patients with neurodegenerative or psychiatric diseases, understanding basic properties of BDNF and associated intracellular processes is imperative. In this review, we revisit the gene structure, transcription, translation, transport and secretion mechanisms of BDNF. We also introduce implications of BDNF in several brain-related diseases including Alzheimer's disease, Huntington's disease, depression and schizophrenia. | Naoki Adachi Tadahiro Numakawa Misty Richards Shingo Nakajima Hiroshi Kunugi | 2014 | World Journal of Biological Chemistry2014，5，4： | 30 |
| 19 | Research progress on silicon/carbon composite anode materials for lithium-ion battery显示文摘Silicon(Si) has been considered as one of the most promising anode material for the next generation lithium-ion batteries(LIBs) with high energy densities, due to its high theoretical capacity, abundant availability and environmental friendliness. However, silicon materials with low intrinsic electric and ionic conductivity suffer from huge volume variation during lithiation/delithiation processes leading to the pulverization of Si and subsequently resulting in severe capacity fading of the electrodes. Coupling of Si with carbon(C) realizes a favorable combination of the two materials properties, such as high lithiation capacity of Si and excellent mechanical and conductive properties of C, making silicon/carbon composite(Si/C) ideal candidates for LIBs anodes. In this review, recent progresses of Si/C materials utilized in LIBs are summarized in terms of structural design principles, material synthesis methods, morphological characteristics and electrochemical performances by highlighting the material structures. The mechanisms behind the performance enhancement are also discussed. Moreover, other factors that affect the performance of Si/C anodes, such as prelithiation, electrolyte additives, and binders, are also discussed. We aim to present a full scope of the Si/C-based anodes, and help understand and design future structures of Si/C anodes in LIBs. | Xiaohui Shen Zhanyuan Tian Ruijuan Fan Le Shao Dapeng Zhang Guolin Cao Liang Kou Yangzhi Bai | 2018 | Journal of Energy Chemistry2018，27，4： | 29 |
| 20 | A review of lithium-ion battery safety concerns:The issues,strategies,and testing standards显示文摘Efficient and reliable energy storage systems are crucial for our modern society.Lithium-ion batteries(LIBs)with excellent performance are widely used in portable electronics and electric vehicles(EVs),but frequent fires and explosions limit their further and more widespread applications.This review summarizes aspects of LIB safety and discusses the related issues,strategies,and testing standards.Specifically,it begins with a brief introduction to LIB working principles and cell structures,and then provides an overview of the notorious thermal runaway,with an emphasis on the effects of mechanical,electrical,and thermal abuse.The following sections examine strategies for improving cell safety,including approaches through cell chemistry,cooling,and balancing,afterwards describing current safety standards and corresponding tests.The review concludes with insights into potential future developments and the prospects for safer LIBs. | Yuqing Chen Yuqiong Kang Yun Zhao Li Wang Jilei Liu Yanxi Li Zheng Liang Xiangming He Xing Li Naser Tavajohi Baohua Li | 2021 | Journal of Energy Chemistry2021，30，8： | 29 |
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